Serratia
Dongyou Liu in Handbook of Foodborne Diseases, 2018
Invasive disease due to Serratia is rarely seen in patients from the community. Furthermore, Serratia is frequently an opportunistic pathogen, affecting individuals with underlying comorbidities including immunosuppression and diabetes. Only <10% of the cases are community-acquired infections. Serratia species have been identified from a variety of clinical specimens. Serratia species are not, however, the dominant pathogens for any particular clinical syndrome, except for ocular infections. The mechanism of inoculation and the source of the pathogen often remain unknown. Infections due to Serratia species have clinical manifestations similar to infections caused by other bacterial pathogens. They are known to cause wound infections; urinary, respiratory tract, and central nervous system infections; keratitis; arthritis; meningitis; endocarditis; osteomyelitis; and bacteremia.1,8,10
Infective endocarditis by Serratia species: a systematic review
Published in Journal of Chemotherapy, 2022
Petros Ioannou, Konstantinos Alexakis, Despoina Spentzouri, Diamantis P. Kofteridis
Serratia spp. were initially considered to be non-pathogenic due to their low virulence among healthy individuals [1]. In the last decades, however, there are increasing reports of these pathogens as causes of invasive disease and nosocomial infections [4]. For example, S. marcescens has been identified as a cause of a wide range of infections, such as respiratory, urinary, or biliary tract infections, catheter-associated infections, and wound infections [1, 4]. Importantly, studies are suggesting an increasing prevalence of Serratia spp. with significant antimicrobial resistance, that may render the treatment of these infections problematic since this is associated with higher mortality [62–64]. Thus, infections by Serratia spp. have drawn the attention of research during the last years to further identify the characteristics of these infections and identify factors associated with mortality [65].
Clinico-microbiological Features and Treatment Outcomes of Serratia Keratitis and Comparison with Pseudomonas aeruginosa Keratitis
Published in Ocular Immunology and Inflammation, 2023
Anahita Kate, Bhupesh Bagga, Lakshmi Prasanna Ponnapati, Shalini Singh, Sahil Shah, Ashik Mohamed, Joveeta Joseph
Serratia is a gram-negative bacillus belonging to the family Yersiniaceae.1 It was considered an innocuous saprophyte until the 1950s, when S. marcescens was found to be the causative pathogen in urinary tract infections and pneumonia.2Serratia species can also cause other systemic infections in the form of osteomyelitis, endocarditis, and arthritis.3 Although S. marcescens is the most common species, infections due to S. liquefaciens, S. rubidaea, S. odorifera, S. ficaria, and S. plymuthica have also been reported.2,4,5 With respect to ocular infections, Serratia species can cause keratitis, conjunctivitis, endophthalmitis, and lacrimal duct infections.6–9
Related Knowledge Centers
- Bacteria
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- Prodigiosin
- Serratia Marcescens
- Bacillus
- Gram-Negative Bacteria
- Facultative Anaerobic Organism
- Serralysin