Burns
Tor Wo Chiu in Stone’s Plastic Surgery Facts, 2018
There is desiccation, corrosion, protein denaturation, liquefactive necrosis and bone decalcification; unrecognised injuries inevitably progress to extensive tissue destruction. Systemic hypocalcaemia leads to cardiac dysrhythmia; refractory (fatal) VF may be induced by the action of F- on the myocardium. Even 2% TBSA involvement may be fatal.
Other neurological diseases
Claude Leray in Dietary Lipids for Healthy Brain Function, 2017
Since the work of Dr. R. Kruse in 1968, many authors have reported the presence of bone decalcification (osteomalacia) and fractures accompanying the long-term treatment of epilepsy with various anticonvulsants. Even if it has not been consistently observed, a link between the disease and low blood vitamin D levels was very frequently reported.
Improved treatment efficacy of risedronate functionalized chitosan nanoparticles in osteoporosis: formulation development, in vivo, and molecular modelling studies
Published in Journal of Microencapsulation, 2019
Shivalingappa Santhosh, Dhrubojyoti Mukherjee, Jayaraman Anbu, Manikanta Murahari, Banala Venkatesh Teja
The femur specimen from each group were transferred to 10% (by weight) neutral-buffered formalin solution followed by bone decalcification, dehydration, and paraffin embedding. Bone fragments of 5 mm (thickness) were separated from the diaphysis, stained with haematoxylin–eosin for microscopic analysis (Bitto et al. 2008).
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