Actinomyces israelii
Faro Sebastian in Infectious Diseases in Obstetrics and Gynecology, 2004
Actinomyces israelii is an anaerobic, Gram-positive, branching filamentous bacterium whose filaments, by their radial attachment to the granule, give the organism its name: actino (radial), myces (mold-like). The diameter of the branching filaments is comparable to that of other bacteria; however, the overall length of the hyphae resembles that of molds measuring hundreds of thousands of microns.
Actinomyces israelii
Faro Sebastian in Infectious Diseases in Obstetrics and Gynecology, 2008
Actinomyces israelii is an anaerobic, gram-positive, branching filamentous bacterium whose filaments, by their radial attachment to the granule, give the organism its name: actino (radial), myces (mold like). The diameter of the branching filaments is comparable to that of other bacteria; however, the overall length of the hyphae resembles that of molds measuring hundreds of thousands of microns.
C18 Branching Gram-Positive Bacteria
Will Irving, Dlawer Ala’Aldeen, Tim Boswell in Instant Notes Medical Microbiology, 2004
Microbiology Actinomyces and Nocardia are branching, nonmotile and slow-growing Gram-positive bacilli. Only a few species cause rare diseases in man.
Proteome analysis of the salivary pellicle formed on titanium alloys containing niobium and zirconium
Published in Biofouling, 2019
Heloisa Navarro Pantaroto, Karina Pintaudi Amorim, Jairo Matozinho Cordeiro, João Gabriel S. Souza, Antônio Pedro Ricomini-Filho, Elidiane C. Rangel, Ana Lúcia R. Ribeiro, Luís Geraldo Vaz, Valentim A.R. Barão
The chemical composition of biomaterials can drive their biological responses; therefore, this in vitro study aimed to evaluate the proteomic profile of the salivary pellicle formed on titanium (Ti) alloys containing niobium (Nb) and zirconium (Zr). The experimental groups consisted of Ti35NbxZr (x = 5 and 10 wt%) alloys, and commercially pure titanium (cpTi); titanium aluminium vanadium (Ti6Al4V) alloys were used as controls. The physical and chemical characteristics of the Ti materials were analysed. The proteomic profile was evaluated by liquid chromatography coupled with tandem mass spectrometry. Bacterial adhesion (2 h) of mixed species (Streptococcus sanguinis and Actinomyces naeslundii) was investigated as colony-forming units (n = 6). This paper reports the finding that salivary pellicle composition can be modulated by the composition of the Ti material. The Ti35NbxZr group showed a significant ability to adsorb proteins from saliva, which can favour interactions with cells and compatibility with the body.
Tongue coating microbiome data distinguish patients with pancreatic head cancer from healthy controls
Published in Journal of Oral Microbiology, 2019
Haifeng Lu, Zhigang Ren, Ang Li, Jinyou Li, Shaoyan Xu, Hua Zhang, Jianwen Jiang, Jiezuan Yang, Qixia Luo, Kai Zhou, Shusen Zheng, Lanjuan Li
Background: The microbiota plays a critical role in the process of human carcinogenesis. Pancreatic head carcinoma (PHC)-associated tongue coating microbiome dysbiosis has not yet been clearly defined.Objective: Our aim is to reveal the bacterial composition shifts in the microbiota of the tongue coat of PHC patients.Design: The tongue coating microbiota was analyzed in 30 PHC patients and 25 healthy controls using 16S rRNA gene sequencing technology.Results: The microbiome diversity of the tongue coat in PHC patients was significantly increased, as shown by the Shannon, Simpson, inverse Simpson, Obs and incidence-based coverage estimators. Principal component analysis revealed that PHC patients were colonized by remarkably different tongue coating microbiota than healthy controls and liver cancer patients. Linear discriminant analysis effect size revealed that Leptotrichia, Fusobacterium,Rothia, Actinomyces, Corynebacterium, Atopobium, Peptostreptococcus, Catonella, Oribacterium, Filifactor, Campylobacter, Moraxella and Tannerella were overrepresented in the tongue coating of PHC patients, and Haemophilus, Porphyromonas and Paraprevotella were enriched in the tongue coating microbiota of healthy controls. Strikingly, Haemophilus, Porphyromonas, Leptotrichia and Fusobacterium could distinguish PHC patients from healthy subjects, and Streptococcus and SR1 could distinguish PHC patients from liver cancer patients. Conclusions: These findings identified the microbiota dysbiosis of the tongue coat in PHC patients, and provide insight into the association between the human microbiome and pancreatic cancer.
Copper Accumulation in Actinomyces Druses During Endometritis After Long-Term Use of an Intrauterine Contraceptive Device
Published in Ultrastructural Pathology, 2002
Ludwig Jonas, Frank Baguhl, Hans-Peter Wilken, Hermann Josef Haas, Horst Nizze
A 32-year-old woman carried a copper intrauterine contraceptive device (IUCD) or intrauterine pessar (IAP) for more than 5 years. She had acyclic menstrual bleedings and underwent a corpus abrasio after explantation of IUCD. The histological study of paraffin sections showed an actinomycotic endometritis with brown to black deposits in or around typical actinomyces druses, but there was no carcinoma. The electron microscopic study of these accumulations by electron energy loss spectroscopy (EELS) in TEM demonstrated copper deposits in the shell and matrix of these druses as well as inside the bacteria. With scanning electron microscopy (SEM) and Energy Dispersive X-Ray Analysis (EDX), the electron-dense accumulations revealed high signals for copper and sulfur, but also of phosphorus and oxygen in a lower extent. This copper accumulation is discussed as an active uptake and concentration by these actinomyces bacteria.
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