Normal Anatomy of the Female Pelvis and Sonographic Demonstration of Pelvic Abnormalities
Asim Kurjak in Ultrasound and Infertility, 2020
However, it should be remembered that leiomyomas are usually easily accessible for palpation, and the diagnosis of clinically significant tumors is in most cases made merely by palpation. Therefore, the need for ultrasound investigation of the fibroma can be easily reduced to cases in that either the palpatory findings are unclear or further information is required (e.g., in obese patients, difficult vaginal examination, a combination of fibroma with other tumors, follow-up of smaller tumors to evaluate more precisely their growth, and more accurate localization of myomatous knots).
Bones, joints, muscles and tendons
Kevin G Burnand, John Black, Steven A Corbett, William EG Thomas, Norman L Browse in Browse’s Introduction to the Symptoms & Signs of Surgical Disease, 2014
Three tumours can arise from this tissue: Benign fibroma is very rare.Fibrosarcoma is a common mesodermal soft tissue malignant tumour.Paget’s recurrent desmoid tumour is less common than fibrosarcoma, locally invasive and often recurrent.
Abdominal wall, hernia and umbilicus
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie in Bailey & Love's Short Practice of Surgery, 2018
This is usually considered by pathologists to be a hamartoma and is more common in women. Some, however, believe it to be a fibroma and possibly the result of repeated trauma. Desmoids have been reported in familial adenomatous polyposis (FAP). Histologically, they contain plasmoidal cell masses resembling giant cells. They undergo central myxomatous change. Surgical excision with a wide margin is required to prevent recurrence, which is a frequent problem.
A rare case of recurrences of multiple ovarian fibrothecoma
Published in Journal of Obstetrics and Gynaecology, 2021
Gianluca Raffaello Damiani, Mario Villa, Giulio Licchetta, Maria Cristina Cesana, Edoardo Dinaro, Matteo Loverro, Giuseppe Muzzupapa, Antonio Pellegrino
According to the World Health Organisation classification, fibromas and thecomas belong to the group of sex cord-stromal tumours, specifically to the subgroup of granulosa-stromal cell tumours. Fibromas and fibrotechomas constitute 1–4.7% of ovarian neoplasms (Chechia et al. 2008). Histologically fibromas are composed of spindle-shaped fibroblastic cells, are collagen-producing, which are not hormonally active. According to 2014 WHO classification, fibromas are considered as benign if they present <4 mitotic figures per 10 HPF, as mitotically active cellular fibroma. Fibrosarcomas are characterised by mitotic activity >4 per 10 HPF (Prat and Scully 1981; Irving et al. 2006). A fibroma could be misdiagnosed as a malign mass when associated with ascites and pleural effusion (Meigs’ syndrome) (Chechia et al. 2008; Paladini et al. 2009; Yen et al. 2013). Elevated CA125 is rare and is associated with Meigs’ syndrome (Scully et al. 1998). The recurrence of ovarian fibroma, often bilateral, is typical of Gorlin syndrome (Scully et al. 1998). Thecomas are mainly composed of theca cells, lipid-laden and may produce oestrogen and could cause abnormal uterine bleeding, be oestrogenic or, rarely, androgenic manifestations if they are hormonally active (Chechia et al. 2008). Fibromas and thecomas occur typically in menopausal women.
Mucinous cystadenoma with fibroma: a rare combination of collision tumour
Published in Journal of Obstetrics and Gynaecology, 2022
Tanisha Singla, Chintamani Pathak, Anam Singh, Gaurav Singla, Swati Singla, Naveen Kumar R.
To correctly diagnose this tumour, one must differentiate it from fibroma with cystic changes and mucinous cystadenofibroma. The presence of columnar lining of the cysts ruled out fibroma with cystic change and absence of glandular structures in fibroma with presence of distinct interface between solid fibrous part and mucinous cystic part ruled out mucinous cystadenofibroma. The absence of transitional epithelium differentiated this tumour from Brenner Tumour with mucinous metaplasia or associated with a mucinous cystadenoma. Also, another important differential diagnosis is composite tumours (Lewin 1987) (e.g. malignant mixed Mullerian tumour) which are characterised by intermingling of different components in one neoplastic mass, as opposed to collision tumours, which show distinct interface between the two components.
Subperiosteal fibroma of the orbit
Published in Orbit, 2018
Andrew J. Rong, Jan P. Ulloa-Padilla, Nathan W. Blessing, David T. Tse, Sander R. Dubovy, Catherine J. Choi
According to Henderson, the diagnosis of an “orbital fibroma” has decreased significantly in frequency since the 1970s following the revised pathologic classification of fibrous tumors.1 The differential diagnosis for these lesions may include solitary fibrous tumors, dedifferentiated liposarcomas, fibrous histiocytomas, malignant nerve sheath tumors, schwannomas, and soft-tissue angiofibromas. In contrast to the malignant lesions listed above, fibromas are highly differentiated, showing few mitotic figures and no histiocytic response. The tumor stains positively with Masson trichrome and variably with Alcian blue. Immunohistochemistry demonstrates negative staining for CD-34 and STAT-6, differentiating it from solitary fibrous tumors and fibrous histiocytomas.2,3 Upon review with newer histologic markers and the use of immunohistochemistry, the initial diagnosis of “orbital fibroma” in many cases has been corrected to more accurate diagnoses such as fibrous histiocytoma and fibrochondroma.1
Related Knowledge Centers
- Benign Tumor
- Dermatofibroma
- Keloid
- Mesenchyme
- Connective Tissue
- Malignancy
- Fibroblast
- Skin Tag
- Fibrosarcoma
- Scar