Cancer of the Breast
Jennifer L. Kelsey, Nancy G. Hildreth in Breast and Gynecologic Cancer Epidemiology, 2019
At the present time, the biologic basis for the association between fibrocystic breast disease and breast cancer is unknown. One possibility is that cystic disease is a pre-malignant condition. Findings from autopsy studies167,168 of women who did not seek care for breast disease indicate that several parts of the breast may contain undiagnosed fibrocystic disease. Also, cancer is just as likely to develop in the breast opposite to the one in which the cystic disease had been diagnosed.147–149 These observations suggest that many possibly premalignant cells are dispersed throughout the breasts of some women with fibrocystic disease; the diagnosed cystic disease may be only the most obvious part of a widely dispersed pathologic process. On the other hand, an abnormal hormonal milieu may exist in some women with fibrocystic disease that makes all breast epithelial cells “premalignant” or susceptible to a carcinogenic factor.
Fibrocystic Breasts/Cystic Mastitis/Mammary Dysplasia
Charles Theisler in Adjuvant Medical Care, 2023
Fibrocystic breasts typically cause swelling, pain, and tenderness that gets worse premenstrually, but can remain throughout the month. The breasts are composed of tissue that feels lumpy, granular, or hard, or has a rope-like texture. The exact cause of this disorder is unknown. Fibrocystic breasts are the most common cause of non-cancerous breast lumps in women between 30 and 50 years of age. It is thought that more than half of women will develop fibrocystic breast disease at some point in their lives, but that many will not have any associated symptoms.
Women’s Health and Nutrition
Mary J. Marian, Gerard E. Mullin in Integrating Nutrition Into Practice, 2017
Fibrocystic breast (sometimes referred to as fibrocystic breast disease, fibrocystic breast condition) is a benign condition in which the breast(s) are lumpy and often swollen and/or painful. For years, it was thought that high fat or high caffeine intake may cause/increase risk for fibrocystic breasts. However, the data has not been compelling to demonstrate a link and further research to identify a diet-related link has not been actively pursued [74,75].
What is the position of testosterone in the care of women?
Published in Climacteric, 2019
Since that time, women have been treated with testosterone for diverse reasons. The most prominent clinical indication has been low sexual desire. Past proposed indications have also included fibrocystic breast disease3 and breast cancer4,5. However, more recently women have reportedly been treated with testosterone for non-traditional indications including ‘hot flushes, sweating, sleep disturbance, heart discomfort, depressive mood, irritability, anxiety, premenstrual syndrome, fatigue, memory loss, menstrual or migraine headaches, vaginal dryness, sexual problems, urinary symptoms including incontinence, musculoskeletal pain and bone loss’6. Whether any of these aforementioned clinical complaints justify treatment of women with testosterone has been contentious.
High prevalence of benign mammary tumors in a rat model of polycystic ovary syndrome during postmenopausal period
Published in Gynecological Endocrinology, 2019
Mahsa Noroozzadeh, Samira Behboudi-Gandevani, Nariman Mosaffa, Maryam Tohidi, Fahimeh Ramezani Tehrani
The incidence of fibrocystic breast disease is 7% in the general population [4]. Previous studies have reported a significant association between PCOS and benign breast diseases (BBD), e.g. fibrocystic breast disease and increased prevalence of BBD in these patients [5,6], in whom this may be due to hormonal imbalances and anovulation, that are involved in the etiology of BBD [4,6].
Related Knowledge Centers
- Breast
- Fibroadenoma
- Fibrosis
- Menarche
- Menstrual Cycle
- Breast Cancer
- Cancer
- Breast Pain
- Breast Cyst
- Breast Mass