Antioxidants
Linda M. Castell, Samantha J. Stear (Nottingham), Louise M. Burke in Nutritional Supplements in Sport, Exercise and Health, 2015
Muscle fatigue is defined as an acute reduction in the ability of a muscle to generate force. Exercise-induced muscle fatigue is a multi-faceted process and the specific causes of fatigue vary. Growing evidence indicates that ROS production is among the most important contributors to muscular fatigue during prolonged submaximal exercise (i.e. events lasting >30 minutes). Interestingly, levels of ROS production in contracting skeletal muscle represent a ‘double-edged sword’. Low levels of ROS in active skeletal muscle are required to achieve optimum force production, while high ROS levels induce oxidative damage to muscle proteins that can diminish muscle force production. Findings from well-controlled animal studies indicate that scavenging ROS via exogenous antioxidants protects skeletal muscle against oxidative damage and delays fatigue during prolonged submaximal exercise. By contrast, antioxidant scavengers are ineffective in delaying muscle fatigue in animals performing high-intensity exercise (Powers and Jackson, 2008).
Assessment for Rehabilitation of COVID-19
Wenguang Xia, Xiaolin Huang in Rehabilitation from COVID-19, 2021
The basic function of respiratory muscles is to provide power for pulmonary ventilation through regular, nonstop contractile and diastolic movements. In pathological conditions, respiratory muscle fatigue and function decline will cause pulmonary ventilation disorders and respiratory failure, even affecting normal life. The main clinical manifestations of respiratory muscle fatigue include: Dyspnea.Changes in breathing patterns, such as rapid shallow breathing, or prolonged exhalation, wheezing, etc.Decrease in diaphragm motion amplitude.Recovery of respiratory muscle function after rest.Changes in lung function; lung capacity and pulmonary ventilation functions, such as vital capacity, tidal volume, maximum ventilatory volume, etc., can be reduced to different degrees when respiratory muscle fatigue occurs.
Muscle
Laurie K. McCorry, Martin M. Zdanowicz, Cynthia Y. Gonnella in Essentials of Human Physiology and Pathophysiology for Pharmacy and Allied Health, 2019
Muscle fatigue is defined as the inability of a muscle to maintain a particular degree of contraction over time. The onset of fatigue is quite variable and is influenced by several factors including: Intensity and duration of contractile activityUtilization of aerobic versus anaerobic metabolism for energyComposition of the muscleFitness level of the individual
Automated detection of muscle fatigue conditions from cyclostationary based geometric features of surface electromyography signals
Published in Computer Methods in Biomechanics and Biomedical Engineering, 2022
Divya Bharathi K, Karthick P. A., Ramakrishnan S.
Muscle fatigue is a condition in which muscles fails to generate the required force. During this condition, the subjects do not feel they could achieve the required movement range (Potvin and Bent 1997). Myoelectric manifestations of muscle fatigue are associated with the alterations in the amplitude and shape of compound motor action potentials which in turn results in the ensemble variations of features of the sEMG signals (Merletti et al. 1990; Gallina et al. 2011). It plays a vital role in the field of sports, rehabilitation and gait analysis. Infact, it is one of the major concerns in myoelectric interface when an experimental protocol is designed. Muscle fatigue is also a major symptom in nearly sixty percent of neuromuscular patients. Repeated fatigue permanently damages the muscle and sometimes it is irreversible (Wan et al. 2017). Thus, diagnosing the muscle fatigue condition at an early stage is crucial (Enoka and Duchateau 2008). To assess this condition, various methods such as isometric strength test, muscle imaging and biopsy are in practice. Surface electromyography (sEMG) is one of the commonly employed method for muscle fatigue analysis (Merletti and Farina 2016).
Effects of lower limb muscle fatigue on gait performance and postural control among individuals with Parkinson’s disease: a review of literature
Published in Physical Therapy Reviews, 2019
Halimatul Abd Ghani, Maria Justine, Haidzir Manaf
The earliest reference to fatigue in PD was made in 1967 [5]. The prevalence of fatigue in PD ranges from 33 to 70% of the total population [6]. It typically occurs at the early stage and worsens as the disease progresses [7]. Fatigue is a normal physiological response to prolonged and intense activity among healthy individuals and is predictable and can be ameliorated with rest, without interfering with the daily activities [8]. However, fatigue is unpredictable for individuals with PD, who respond poorly to rest; thus, daily activities are restricted [9]. Fatigue can be classified as peripheral or central [10]. Peripheral fatigue is the feeling of exhaustion due to repetitive contraction of the muscles; this type is known as muscle fatigue or physical exercise fatigue [11]. An early study defined muscle fatigue as a reduction of the maximal power or force that can be generated by the involved muscle and gradually develops immediately after prolonged physical activity [12]. Similarly, the term of performance fatigability refers to a decline in peak force or torque after performing an exercise intervention among neurologic illnesses [13]. Thus, individuals with PD suffer from tremors and bradykinesia, which lead to muscle fatigue [7]. Fatigue is the most disabling of the PD symptoms and has a significant effect on the quality of life [14].
Prevalence of musculoskeletal disorders in anesthesiologists in Ismailia Governorate
Published in Egyptian Journal of Anaesthesia, 2023
Eslam Albayadi, Abelrahman Soliman, Wesam F. Alyeddin
Risk factors for the development of musculoskeletal disorders included the need for excessive bending and twisting, poor work ergonomics that needs improvement, poorly optimized patient position before specific procedures, and prolonged working hours per week. This was emphasized by a previous study reporting repeated maneuvers and long forceful positions as work-related risk factors for developing WRMSDs [16]. An earlier study reported that work ergonomics were suboptimal by 69.1% of the participants [14]. It has been reported that working in the outpatient clinic for>16 hours/week was associated with increased head and neck pain [17]. This would be explained by prolonged working hours acting as a cause of muscle fatigue and exhaustion without enough time to recover [18]. The body must maintain a neutral position at work. Awkward positions and sustained static postures cause strain on the musculoskeletal system and body fatigue [19]. Accordingly, ergonomics education during medical training was recommended to change physicians’ behavior and reduce the developing symptoms [6].
Related Knowledge Centers
- Action Potential
- Calcium
- Exercise
- Muscle Contraction
- Sarcoplasmic Reticulum
- Brain
- Muscle Cell
- Nerve
- Plank
- Strength Training