Cancer in Los Alamos
Steven E. Rigdon, Ronald D. Fricker in Monitoring the Health of Populations by Tracking Disease Outbreaks, 2020
This chapter looks at the problem of trying to determine whether there is an unusual incidence of a chronic, non-communicable disease, namely cancer. In 1990 Tyler Mercier, a sculptor from Los Alamos County (LAC), worked as a volunteer on a project to monitor radiation around the town of Los Alamos. While he was performing this task he heard from several people who told him about clusters of cancer, especially brain cancer. For much of the study, lung cancer in men was significantly lower in LAC. The spike in liver cancer, which is rather rare, occurred when there were four cases in 1981 and 1982. Cancer incidence was higher for LAC than for New Mexico, but the reverse was true for cancer mortality. Given that cancer occurs seemingly at random makes it difficult to detect a change in the cancer risk.
Statistical Analysis of the Pre- and Post-Surgery in the Healthcare Sector Using High Dimension Segmentation
Rashmi Agrawal, Jyotir Moy Chatterjee, Abhishek Kumar, Pramod Singh Rathore, Dac-Nhuong Le in Machine Learning for Healthcare, 2020
This chapter presents the achievements of the set objectives and the comparative performance evaluations and simulation of experimental results. The researcher discusses the damaged cells of the mind due to the abnormalities of the mobile. The sampling collections are used for the have a look at consists of clinical mind snap shots for human being. The researcher will almost implement and simulate the experiments of to the testing on human being and their mind tissues. The purpose of using a set of tools to work with light field images in MATLAB is to decode, calibrate correct, correct color, filter basic images, and visualize light field images. The research closes with a discussion of the challenges of the deep learning method in relation to medical imaging and the research problem. The researcher describes the statistical results of brain cancer through an interface of Magnetic Resonance Imaging-four-dimensional photo segmentation.
Integrative hyperthermia treatments for different types of cancer
Clifford L. K. Pang in Hyperthermia in Oncology, 2015
Modern cancer therapy emphasizes integrative treatments. With the transformation of the medical model from biomedical model to biopsychosocial medical model, cancer therapy is no longer a single treatment for diseases but is the best mode that stresses participation of a variety of means and disciplines and is people-oriented. The common superficial tumors are lymph node metastases, thoracic and abdominal wall metastatic carcinoma, breast cancer, vulvar cancer, malignant melanoma, and so on. As intracranial cancer hyperthermia may increase the risk of cerebral edema, some therapeutic measures for reducing cerebral edema and intracranial pressure need to be taken before treatment of patients accompanied with cerebral edema or high cranial pressure. The syndrome of phlegm dampness and stasis is commonly seen in brain cancer patients. Intracranial cancer hyperthermia is mainly local hyperthermia. Oral cancer is a general term for malignant tumors occurring in the oral cavity. Most oral cancers are squamous cell carcinomas.
I’m Still Me: Inspiration and Instruction from Individuals with Brain Cancer
Published in Journal of Health Care Chaplaincy, 2017
Katherine M. Piderman, Jason S. Egginton, Cory Ingram, Ann Marie Dose, Timothy J. Yoder, Laura A. Lovejoy, Spence W. Swanson, James T. Hogg, Maria I. Lapid, Aminah Jatoi, Megan S. Remtema, Beba S. Tata, Carmen Radecki Breitkopf
Individuals with brain cancer face many challenges, including threats to cognition, personality, and sensory and motor functioning. These can alter one’s sense of identity and result in despair. Chaplain-led spiritual interviews were conducted with 19 patients with brain cancer as part of a larger spiritual legacy intervention called “Hear My Voice.” The majority was female (58%), married (68%) and had aggressive/advanced tumors (63%). Participants were 22–68 years of age and expressed the following religious affiliations: Protestant (42%), Catholic (21%), Muslim (5%), and none (32%). Framework analysis was applied to reduce and understand the interview data. Primary codes were relationships with: God or the spiritual, others, and self. Brain cancer was reported to deepen and enrich patients’ commitment to these relationships. Struggle and grief were also revealed. Results suggest the continued vitality, growth and generativity of these participants and provide insight for chaplains and others on the medical team.
A Pilot Case-Cohort Study of Brain Cancer in Poultry and Control Workers
Published in Nutrition and Cancer, 2014
S. Gandhi, M. Felini, H. Ndetan, K. Cardarelli, S. Jadhav, M. Faramawi, E. Johnson
We conducted an exploratory study to investigate which exposures (including poultry oncogenic viruses) are associated with brain cancer in poultry workers. A total of 46,819 workers in poultry and nonpoultry plants from the same union were initially followed for mortality. Brain cancer was observed to be in excess among poultry workers. Here we report on a pilot case-cohort study with cases consisting of 26 (55%) of the 47 brain cancer deaths recorded in the cohort, and controls consisting of a random sample of the cohort (n = 124). Exposure information was obtained from telephone interviews, and brain cancer mortality risk estimated by odds ratios. Increased risk of brain cancer was associated with killing chickens, odds ratio (OR) = 5.8 (95% confidence interval, 1.2–28.3); working in a shell-fish farm, OR = 13.0 (95% CI, 1.9–84.2); and eating uncooked fish, OR = 8.2 (95% CI, 1.8–37.0). Decreased risks were observed for chicken pox illness, OR = 0.2 (95% CI, 0.1–0.6), and measles vaccination, OR = 0.2 (95% CI, 0.1–0.6). Killing chickens, an activity associated with the highest occupational exposure to poultry oncogenic viruses, was associated with brain cancer mortality, as were occupational and dietary shellfish exposures. These findings are novel.
Therapeutic cell carriers: a potential road to cure glioma
Published in Expert Review of Neurotherapeutics, 2014
Jacob S Young, Julius W Kim, Atique U Ahmed, Maciej S Lesniak
Many different experimental molecular therapeutic approaches have been evaluated in an attempt to treat brain cancer. However, despite the success of these experimental molecular therapies, research has shown that the specific and efficient delivery of therapeutic agents to tumor cells is a limitation. In this regard, cell carrier systems have garnered significant attraction due to their capacity to be loaded with therapeutic agents and carry them specifically to tumor sites. Furthermore, cell carriers can be genetically modified to express therapeutic agents that can directly eradicate cancerous cells or can modulate tumor microenvironments. This review describes the current state of cell carriers, their use as vehicles for the delivery of therapeutic agents to brain tumors, and future directions that will help overcome the present obstacles to cell carrier mediated therapy for brain cancer.
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