Alien Hand Syndrome
Alexander R. Toftness in Incredible Consequences of Brain Injury, 2023
The name of this disorder, alien hand syndrome, works well in describing its symptoms. The disorder has also been called Strangelovian hand (or Dr. Strangelove syndrome) after the titular character who had some of the symptoms in the movie Dr. Strangelove (Kubrick, 1964). However, the name alien hand syndrome captures the imagination and is the more popular way of referring to the disorder, as it is a memorable name for a memorable diagnosis.
Treatment-related transient splenial lesion of the Corpus Callosum in patients with neuropsychiatric disorders: a literature overview with a case report
Published in Expert Opinion on Drug Safety, 2020
Giovanna Cirnigliaro, Ilaria Di Bernardo, Valentina Caricasole, Eleonora Piccoli, Barbara Scaramelli, Simone Pomati, Chiara Villa, Leonardo Pantoni, Bernardo Dell’Osso
From a clinical point of view, the SCC lesion can be accompanied by neurological symptomatology. Most cases present with epileptic seizures [26]. Cases of alien hand syndrome following corpus callosum infarction [27], along with a transient-localized lesion of SCC in a child [28], have been described. A case report documented the concomitant onset of a neuroleptic malignant syndrome [16]. An in-depth analysis of these cases is needed to understand the role CLOCCs play across various clinical manifestations reported. In the field, data is likely due to the benign nature of transient SCC lesions and the common complete reversion of neurological symptoms, when present. In addition, asymptomatic SCC lesions may not be recognized in clinical practice unless MRI is performed for other reasons. Therefore, it currently does not seem possible to clarify the exact correlation between SCC lesions and neurological symptoms. Finally, although the overall symptoms of most patients with CLOCCs tend to subside with a good outcome, patients with any clinic-radiological features tend to need longer hospitalization for diagnostic investigations with or without neurological sequelae [29].
Alien hand syndrome – a rare presentation of stroke
Published in Journal of Community Hospital Internal Medicine Perspectives, 2020
Kelly Le, Christine Zhang, Lisa Greisman
Diagnosis for this patient was alien hand syndrome. This syndrome occurs more often when patient is fatigued, stress, or has divided attention between concurrent activities. [2] AHS is divided into 3 variants: frontal, callosal and posterior based on their presentations and locations of brain impairment. The posterior variant can be seen after infraction in the thalamic, occipital, and parietal region of the brain [2], while callosal variant occurs after callosal injury and frontal variant after supplemental motor area, cingulate region, or corpus callosum injury.