How much is too much for venous malformation management?
Byung-Boong Lee, Peter Gloviczki, Francine Blei, Jovan N. Markovic in Vascular Malformations, 2019
They usually present at childhood or early adulthood with functional or cosmetic symptoms related to their size and location, including pain, reduced joint mobility, and skeletal deformity.3–6 On examination, they are soft and compressible masses with blue discolorations of the skin. They characteristically decompress with elevation and local compression and enlarge on Valsalva maneuver. Palpable phleboliths and thrombi may also be present. They can cross tissue planes and invade adjacent tissues, including fat, muscle, tendon, and even bone. Joint swelling can be caused by venous engorgement, localized thrombosis/thrombophlebitis, mass effect, or local hemorrhage. Any connection to the deeper limb venous system can also precipitate the risk of deep vein thrombosis.3–5
Temporomandibular Joint Disorders
John C Watkinson, Raymond W Clarke, Terry M Jones, Vinidh Paleri, Nicholas White, Tim Woolford in Head & Neck Surgery Plastic Surgery, 2018
Diagnosis is from a history of pain and swelling localized to the area of the joint, with acute onset limitation of movement. The patient will have generalized signs of an infective process with pyrexia, rigors, sweating (particularly night sweats) and malaise. They may also have signs and symptoms of other joint involvement. Locally there will be the signs of acute inflammation with tenderness over the joint, swelling, redness and heat. There may be additional cervical lymphadenopathy and tenderness over the mastoid if there is middle ear involvement.
Rheumatology for general practitioners
Maneesh Bhatia, Tim Jennings in An Orthopaedics Guide for Today's GP, 2017
Check for tender ‘fibromyalgia’ points. These 18 points are located at the back of the cervical spine, between the shoulder blades and around the shoulders and trochanteric bursa. Fibromyalgia is diagnosed if there are 11 or more positive points. Physical examination is usually normal, and there is a striking absence of joint swelling or inflammation despite joint pains.
Predictive role of laboratory markers and clinical features for recurrent Henoch-Schönlein Purpura in childhood: A study from Turkey
Published in Modern Rheumatology, 2020
Şule Gökçe, Zafer Kurugöl, Güldane Koturoğlu, Aslı Aslan
The epidemiological and demographic data including age, gender, seasonal contact time were analyzed. Previous infections, vaccinations, and insect bites were all recorded as provided they were within two weeks prior to the first symptom. Fever was considered to be present if the temperature was >37.7 °C. Renal involvement was defined as follows: Microscopic hematuria was defined when the urine test result was > 5 erythrocytes/mm3; gross hematuria was defined when blood in the urine could be seen with the naked eye. Severe nephropathy was considered to be present when the patient had 1 of the following findings: nephrotic syndrome: defined as plasma albumin level under 25g/L and either 1g of proteinuria/d per m2 of body surface area in children, with or without the presence of edema; or acute nephritic syndrome that was defined as hematuria with at least 2 of the following features; hypertension, elevated plasma urea or creatinine serum levels, and oliguria. Rash location means purpura mainly concentrated in parts of the body. The joint involvement was described as the presence of joint swelling and/or limitation of joint movement. Gastrointestinal involvement was defined as bowel angina (characterized by the presence of diffuse abdominal pain), gastrointestinal bleeding (melena or hematochezia or the child had a positive stool Guaiac test), and nausea and vomiting in the context of the clinical duration of vasculitis. Stomachache and hematemesis also support gastrointestinal involvement.
Combination therapy of ginsenoside compound K and methotrexate was efficient in elimination of anaemia and reduction of disease activity in adjuvant-induced arthritis rats
Published in Pharmaceutical Biology, 2020
Jingyu Chen, Wu Wang, Mengya Jiang, Mei Yang, Wei Wei
To evaluate the severity of arthritis, global assessment, arthritis index, swollen joint count, and paw volume were evaluated. From the day 12, two observers who were blinded to the groups evaluated these indicators. Global assessment was based on symptoms in different parts of rats, including ear, nose, tail, and paws (Chen et al. 2018). Each rat paw has five phalanx joints and one ankle or wrist joint; the number of swelling joints was counted. Degree of joint swelling was recorded and scored as arthritis index (Wu et al. 2007). The secondary inflammatory paw (left hind) swelling of rats was evaluated at day 0, 12, 15,18, 21, 24, 27 using a Paw Volume Metre YLS-7A (Equipment station of Academy of Medical Sciences, Shandong, China). Paw volume (△mL)=paw volume (day 12, 15,18, 21, 24, 27) – paw volume (day 0).
Anti-citrullinated protein antibodies and arthritis in Sjögren’s syndrome: a systematic review and meta-analysis
Published in Scandinavian Journal of Rheumatology, 2019
N Molano-González, E Olivares-Martínez, JM Anaya, G Hernández-Molina
The characteristics of the studies (4–8, 13–17) are summarized in Tables 1 and 2. All the patients included in these studies fulfilled the American–European Consensus Group (AECG) classification criteria for pSS and none of the studies evaluated children. All the studies were performed in rheumatological referral centres, and six were from Europe (4–6, 8, 14) and four from Asia (7, 15–17). Four studies did not report the disease duration (7, 13, 14, 17); in the rest of them, it ranged from 2.4 years to 8.8 years. Half of the studies had a transversal design (4–6, 14, 15) and the rest were longitudinal (7, 8, 16, 17). Among these studies, the median time of follow-up was not mentioned, except in Iwamoto’s study (16) which had a follow-up of 1.83 ± 0.88 years. Most of the studies defined arthritis as non-erosive joint swelling (4–8, 13, 15–17); in two studies, the presence of arthritis was also evaluated by ultrasound findings in all the patients (7) or in the case of doubt after the clinical and X-ray evaluation (8).
Related Knowledge Centers
- Arthrocentesis
- Pus
- Septic Arthritis
- Ultrasound
- Joint
- Infection
- Gout
- Knee Effusion
- Fat Pad Sign
- Hematologic Disease