Clinical applications of hyperthermia in cancer treatments
Clifford L. K. Pang, Kaiman Lee in Hyperthermia in Oncology, 2015
After the medium-high temperature whole-body hyperthermia, there may be side reactions as follows: (1) Burns usually appear in the lower abdomen, front inner side of thigh, blood pressure sleeve location on upper limb, convex position of sacroiliac, heel, and occiput, mainly showing phlyctena, with area <2 cm2, for which a conventional treatment on burns should be applied. (2) Cold sores can appear around the lips within 1–3 days after therapy, for which special treatment is not necessary. (3) The general asthenia can continue for 3–7 days, for which no special treatment is required. (4) A burning sensation during urination may occur for 1–2 days; it is suggested to carry out an examination if it lasts beyond 2 days. (5) The body temperature may rise after therapy to as high as 39°C for some individuals, but no special treatment is necessary for such condition.
Micropigmentation Applied to Oncology Patients
Paloma Tejero, Hernán Pinto in Aesthetic Treatments for the Oncology Patient, 2020
One week before performing a treatment, the patient will be informed that he or she must carry some specific preventive care, such as the following: Prevent cold sores (only in the case of micropigmentation on lips). You should consult with your doctor or apply the preventive measures described earlier.Do not sunbathe or be exposed to ultraviolet A (UVA) rays.Do not perform aesthetic treatments, or medical-aesthetic or surgical interventions in the area of treatment.
Infection
Janet M Rennie, Giles S Kendall in A Manual of Neonatal Intensive Care, 2013
Staff with a current infectious disease such as a respiratory illness, boils, gastroenteritis or weeping dermatitis should be excluded from the unit. Staff with cold sores or herpetic whitlows should cover them, treat with aciclovir and cannot work in a clinical area until the lesions have crusted over. Mothers with wound infections, cold sores, vaginal discharge or known pathogens on their high vaginal swab (HVS) should be allowed in, but any exposed lesions should be covered and their hand washing should be supervised and particularly fastidious. Topical aciclovir should be applied to any cold sores. Mothers of babies with Listeria are inevitably faecal carriers and should be isolated themselves, as should their affected baby.
Twenty years since the Herpetic Eye Disease Study: Lessons, developments and applications to clinical practice
Published in Clinical and Experimental Optometry, 2021
Sana Arshad, Constantinos Petsoglou, Taehwan Lee, Abdullah Al-Tamimi, Nicole A. Carnt
In reactivation of latent infection, HSV travels back down a nerve via anterograde axonal transport to the surface of the body where it replicates.47 HSV can recur either at the original site of infection or at any other site that is innervated by the infected ganglion. It is most typical for the virus to surface in areas that are dense with sensory receptors such as the oral mucosa and lips, presenting as lesions commonly known as cold sores, fingertips (paronychia), nasal skin lesions, and the cornea. The most common method of infection to the cornea for HSV is through the ophthalmic branch of the trigeminal ganglion into the eye resulting in HK. However, HK can also occur through primary infection (including dendritic ulceration) where HSV-1 either directly infects the surface of the eye or through transfer of HSV-1 infection from the orofacial region.3
Critical roles of adherens junctions in diseases of the oral mucosa
Published in Tissue Barriers, 2023
Christina Kingsley, Antonis Kourtidis
A family of viruses that manifest in the oral cavity are Herpes viruses, of which several types are found in humans. Herpes simplex virus type 1 (HSV-1) and Herpes simplex virus type 2 (HSV-2) cause common opportunistic viral infections. Other types of herpesviruses are Varicella zoster, Cytomegalovirus, and Epstein-Barr Virus. HSV-1 reactivates and replicates in the oral epithelium, leading to localized painful vesicles, colloquially often referred to as “cold sores”. These viruses cause lifelong infections and establish latency with periodic reactivations. HSV-1 viruses often spread by close contact and through sharing saliva and are highly infectious, while most people infected are asymptomatic. To infiltrate the cell, HSV-1 viral particles utilize nectin-1 as their cell surface receptor (Figure 2). In this case, disruption of AJs can expose nectin-1, allowing HSV to bind to it and further infiltrate the tissue.93 Therefore, the integrity of the AJs in the oral epithelium can determine the course of HSV infection, opening up an important area of future study.94
Herpes simplex virus type 1 and Alzheimer’s disease: link and potential impact on treatment
Published in Expert Review of Anti-infective Therapy, 2019
Roberta Mancuso, Mariaconcetta Sicurella, Simone Agostini, Peggy Marconi, Mario Clerici
Herpes simplex virus (HSV) type 1 and type 2 are human neurotropic, host-adapted pathogens whose lifestyle is based on a long-term dual interaction with the infected host that can establish both lytic and latent infections [16]. These viruses establish latent infections in sensory ganglia; such infections can undergo reactivations that can be either asymptomatic or symptomatic. In this case, cold sores, keratitis, blepharitis, meningitis, encephalitis, genital infections or systemic and severe conditions in immune compromised patients can be observed [17]. Dissemination is very common in human communities owing to latent infection, periodic reactivation, and asymptomatic virus shedding. HSV is a highly prevalent infection worldwide: 67% of the population under the age of 50 was shown to be infected with HSV-1 and 11% harbors HSV-2 [18]. The HSV-1 infection is generally acquired during childhood, although during the past 20 years in developed countries a decreased trend of seroprevalence has been observed in adolescent and young adults [19].
Related Knowledge Centers
- Blister
- Dormancy
- Herpes
- Herpes Simplex Virus
- Trigeminal Ganglion
- Ulcer
- Lymphadenopathy
- Viral Disease
- Lip
- Sunlight