Treatment of cholera
Dinesh Kumar Jain in Homeopathy, 2022
With the success of the cholera treatment homeopathy became very popular throughout the world. But it was the wrong popularity of homeopathic treatment. I am describing the fact here. Cholera is an acute diarrheal disease caused by Vibrio cholerae. Studies have shown that more than 90% of cholera cases are mild. In severe cases of cholera, painless watery diarrhea is followed by vomiting. The patient soon reaches a stage of collapse because of dehydration. Death may occur at this stage due to dehydration and acidosis. If death does not occur, the patient begins to show signs of improvement. The classical form of severe cholera occurs in only 5–10% of cases. In the rest the disease tends to be mild, characterized by diarrhea with or without vomiting. Generally, mild cases recover in one to three days (Park, 1997, pp. 163–170).
Digestion
Lisa Jean Moore, Monica J. Casper in The Body, 2014
Cholera is an acute diarrheal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae. Annually, there are an estimated three to five million cholera cases globally, which lead to 100,000–120,000 deaths. The bacterium’s short incubation period, of two hours to five days, enhances the potentially explosive pattern of outbreaks. Epidemiologists state that cholera is endemic in many countries, which means that the disease is constantly present to greater or lesser extent in a particular locality. One would expect to find a consistent rate of the disease, and thus it is managed according to that rate. It is worth noting that cholera can be treated very simply with clean drinking water, which would prevent almost all deaths.
A brief history of pandemics
Edward M. Rafalski, Ross M. Mullner in Healthcare Analytics, 2022
The third major mode of transmission, oral ingestion from a common source, is best exemplified by the cholera pandemics of the 19th century (Table 2.1). Cholera, a disease characterized by acute watery diarrhea, is caused by the bacterium Vibrio cholerae. It had been endemic for centuries in the Ganges basin of India, but first spread globally beginning in 1817 through Asia, and thence into India, Russia, Europe, and the Americas. Six subsequent pandemics occurred over the next 130 years, and it continues to cause epidemics worldwide affecting millions annually [9]. The third cholera pandemic is best known for the observations of the epidemiologist John Snow in England, who demonstrated the waterborne nature of the illness by removing the pump handle on a well in one district, and comparing disease there to other city districts. The current strain causing epidemics, known as the “El Tor biotype,” first arose in “quarantine stations” in El Tor, Egypt where travelers back from Mecca after attending the Hajj were kept in squalid conditions for weeks or months prior to being allowed into European countries [9].
Vibrio cholerae lipopolysaccharide loaded chitosan nanoparticle could save life by induction of specific immunoglobulin isotype
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Mahdi Fasihi-Ramandi, Hamideh Ghobadi-Ghadikolaee, Sajjad Ahmadi-Renani, Ramezan Ali Taheri, Kazem Ahmadi
Cholera disease is the life threatening diarrhea caused by Vibrio cholerae (V. cholerae). This disease is a topical infection of the small intestine and the therefore, the topical defense might be a main determinant of protection against recurrent infection (Onischenko et al. 2016). In general, following a natural infection by the V. cholerae, similar to the parenteral injection of killed V. cholerae whole cells vaccine, circulation of specific antibodies could be detected. These antibodies that rose in V. cholerae whole cells when exposed to people were against LPS, outer membrane proteins, flagellum, etc. Furthermore, removal of anti-LPS antibody from these polyclonal antiserums resulted in substantial loss of its protective effect against experimental cholera (Rahman et al. 2013, Uddin et al. 2014).
Thomas Mann’s depiction of neurosyphilis and other diseases
Published in Journal of the History of the Neurosciences, 2018
François Boller, Nicoletta Caputi
The other great plague Mann describes is cholera, which permeates his novel Death in Venice. Cholera is an acute diarrheal infection caused by ingestion of food or water contaminated with the bacterium Vibrio cholerae. Its origins are ancient, but the rapid modernization during the Industrial Revolution of the mid-nineteenth century propelled the diffusion of the disease and cholera spread across the world from its original reservoir in the Ganges delta in India. In Mann’s novel, the main character, Gustav von Aschenbach, is an admired author, appreciated for the formal perfection of his work. During his stay in Venice, he encounters a Polish family and begins to be attracted and fascinated by the young teenager Tadzio. Despite warnings of a cholera epidemic, Aschenbach chooses to stay in Venice and sacrifices his life to the beauty of Tadzio.
Mucosal and systemic immune responses to Vibrio cholerae infection and oral cholera vaccines (OCVs) in humans: a systematic review
Published in Expert Review of Clinical Immunology, 2022
Akshayata Naidu, Sajitha Lulu S
Cholera is a water-borne enteric disease caused by Vibrio cholerae, a gram-negative bacterium, as it hijacks the gut epithelia and induces a massive efflux of water and minerals in infected subjects characterized by ‘rice-water stool’ diarrhea. Millions of cases occur annually in Asia and in sub-Saharan Africa with a mortality rate of as low as less than 1% and as high as 50% in areas where treatment facilities are not available[1]. The recent background paper by WHO suggests that majority of cholera cases come from cholera endemic countries, and from countries and regions undergoing humanitarian crisis and hence facing poor hygienic conditions and periodic epidemics[2]. In fact, the ‘largest and fastest’ cholera outbreak in the last 80 years was recorded in Yemen in 2017 occurring parallelly with the war-induced humanitarian crisis [3].
Related Knowledge Centers
- Bacteria
- Dehydration
- Vibrio Cholerae
- Vomiting
- Small Intestine
- Diarrhea
- Infection
- Strain
- Cramp
- Electrolyte Imbalance