Plant-Based Adjunct Therapy for Tuberculosis
Namrita Lall in Medicinal Plants for Cosmetics, Health and Diseases, 2022
The frequent occurrence of liver toxicity during TB treatment is a concern. Withdrawal of treatment by patients and the development of multidrug resistant (MDR) TB is usually the result of hepatotoxicity (Ramappa and Aithal, 2013). The liver is responsible for regulating various physiological processes and a source of effective enzymes that transform foreign molecules to metabolize and detoxify several heterochthonous or autochthonous chemicals (Bedi et al., 2016). A natural plant-based anti-TB drug with hepatoprotective activity is Liv52, a polyherbal formulation that has been used for many years for various hepatic disorders. The main principle herbs in this preparation include Capparis spinosa L., Solanum nigrum L., Achillea millefolium L., Tamarix gallica L., Cassia occidentalis L., Cichorium intybus L. and Terminalia arjuna (Roxb. ex DC.) Wight & Arn. A meta-analysis conducted by Dange (2010) showed that the outcome of including Liv52 in the treatment of patients who suffered from various forms of TB, including pulmonary TB, extrapulmonary TB, miliary TB, tuberculous cervical lymphadenitis and meningitis resulted in significant improvements as a hepatoprotective drug. Furthermore, it aided in the weight gain of anorexic patients (Dange, 2010).
Tropical infections and infestations
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie in Bailey & Love's Short Practice of Surgery, 2018
Although tuberculosis can affect all systems in the body, in the tropical world the surgeon is most often faced with tuberculosis affecting the cervical lymph nodes and the small intestine. Therefore, in this chapter tuberculous cervical lymphadenitis and tuberculosis of the small bowel will be described.
Chapter 9: Pediatric tuberculosis
Published in Canadian Journal of Respiratory, Critical Care, and Sleep Medicine, 2022
Rachel Dwilow, Charles Hui, Fatima Kakkar, Ian Kitai
Any extra-pulmonary site may be involved, most commonly extrathoracic lymph nodes. Mycobacterial cervical lymphadenitis in children is most commonly due to non-tuberculous mycobacteria. However, lymph node disease due to M. tuberculosis should be strongly considered in those with risk factors. TB lymphadenitis is more common in older children and adolescents (Table 3).20 Miliary/disseminated disease and CNS disease, the most life-threatening forms of TB, are more likely to occur in children <2 years old, children who were not identified as contacts and the immunocompromised. In Canada, CNS TB has occurred more often in children ≥5 years old (Table 3), possibly reflecting the influence of contact tracing and contact management.
Related Knowledge Centers
- Lymph Node
- Lymphadenopathy
- Mycobacterium Tuberculosis
- Tuberculosis
- Mycobacterium
- NONtuberculous Mycobacteria
- Immunodeficiency
- Mycobacterium Scrofulaceum
- HIV/AIDS
- Signs & Symptoms