Milk quality in peri-urban Dar es Salaam: cream on top or tip of the iceberg?
Kristina Roesel, Delia Grace in Food Safety and Informal Markets, 2014
Previous studies in central Tanzania found that bacterial contamination of milk and dairy products with Staphylococcus aureus was common. S. aureus occurs frequently as part of the normal microflora on the skin and in the nasal passages of humans and other mammals. However, it can cause pimples, skin infections, abscesses, pneumonia and even blood poisoning. Of particular relevance to the food processing industry is the ability of some strains of S. aureus to produce toxins that cause staphylococcal food poisoning, which ranks as one of the most prevalent causes of gastroenteritis worldwide. Within one to six hours after consuming contaminated food, staphylococcal food poisoning can cause diarrhoea, vomiting and cramps. People who are otherwise healthy recover rather quickly, but in susceptible individuals it can be fatal.
Catalog of Herbs
James A. Duke in Handbook of Medicinal Herbs, 2018
Toxicity — Safrole, having produced liver tumors in rats, has, like oil of sassafras, been banned because of its purported hepatotoxicity. Oil of sassafras is said to produce dermatitis in sensitive individuals. Morton46 adds that the decoction makes pimples come out on arms and body if the root is used before it is aromatic. Heliotropin, a safrole derivative, used in cosmetics, has been reported to cause dermatitis.6 Safrole (chemically like myristicin and asarone) is suspected of being hallucinogenic in large doses (carcinogenic and hepatotoxic).11 A teaspoonful of oil produced vomiting, dilated pupils, stupor, and collapse in a young man. Its use has caused abortion.2 Safrole-free sassafras extract (§ 172.580) and safrole-free sassafras leaves and extracts (§ 172.510) are approved for food use. Safrole, sassafras, and sassafras oil are prohibited from use in foods.29 Safrole is also reported from basil, black pepper, mace, and nutmeg. After quoting a nice verse from the “Spring Ode” by Donald Robert Perry Marquis:
Acne Vulgaris
Charles Theisler in Adjuvant Medical Care, 2023
Acne vulgaris is the most prevalent chronic skin disease in the U.S. It is the most common chronic skin disorder among the adolescent age group, affecting 90%–95% of the midteen population. Acne also affects young adults and can persist into the 30s and 40s.1 It is characterized by areas of pimples (e.g., blackheads, whiteheads, pustules, cysts, etc.), greasy skin, and possible scarring. Acne is primarily thought to be due to overactivity of the sebaceous (oil) glands in the skin where sebum and dead skin block pores and become inflamed. Outbreaks tend to occur where sebaceous glands are most numerous on the face and upper chest, back, or shoulders. Complications include scarring, cutaneous abscesses, and acneiform lesions.
Thermosensitive gel based on cellulose derivative for topical delivery of propolis in acne treatment
Published in Pharmaceutical Development and Technology, 2022
Fernanda Belincanta Borghi-Pangoni, Jéssica Bassi da Silva, Rafaela Said dos Santos, Ana Paula Trevisan, Francyelle Carolyne de Castro Hott, Marcelly Chue Gonçalves, Renata Katsuko Takayama Kobayashi, Maria Vitória Felipe de Souza, Marcia Edilaine Lopes Consolaro, Lidiane Vizioli de Castro-Hoshino, Mauro Luciano Baesso, Marcos Luciano Bruschi
Acne vulgaris is among the two main skin disorders globally, and it is the 8th in prevalence (Garg 2016; Taleb et al. 2018; Mancuso et al. 2020). This dermatological disease occurs on the upper back, neck region, chest, and mainly on the face, and it can lead to social and psychological problems for the patient. It is characterized by abnormal sebum secretion, with bacterial growth, inflammation, follicular epithelial desquamation, and immunological responses of the host (Castro et al. 2011; Patel and Prabhu 2020). The proliferation of microorganisms like Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis, is considered one of many factors that can induce the inflammatory process (Gollnick et al. 2003; Bojar and Holland 2004; Barbosa et al. 2014; Mazzarello et al. 2018). Acne can be classified into mild (comedones and pimples without inflammation), moderate (presence of papules, pustules, and some inflammation), and severe with the presence of previous characteristics and painful cystic nodules, which can form skin scars (Jacob et al. 2001; Patel and Prabhu 2020).
Changes in T lymphocyte subsets in peripheral blood of patients with middle-advanced cervical cancer before and after nimotuzumab combined with concurrent chemoradiotherapy
Published in Journal of Obstetrics and Gynaecology, 2023
Man Ao, Pengyu Li, Dongxue Sun, Xiaojun Li, Shulei Xu, Yuntao Hao
Cervical cancer (CC) is regarded as the 4th most widespread malignancy and primary cause of cancer-associated deaths in women throughout the world, especially in low-income countries (Castle et al. 2021). Recent investigations have to come to light indicating that approximately 99.7% of CC cases are attributed to persistent high-risk human papillomavirus (HPV) infection (Okunade 2020). Fortunately, CC is regarded as highly preventable and can be cured if detected at early stages (Pimple & Mishra 2019). However, only a minority of CC patients are detected at the early stage (13% at stage I), and the vast majority are diagnosed at mid-to-late stages (35% at stage II, 44% at stage III, and 8% at stage IV) (Gopu et al. 2021), which are attributed to its asymptomatic nature at early stages. Meanwhile, treatment modalities largely depend on CC severity at diagnosis and resources available locally, with conservative and fertility-preserving surgery serving as the standard treatment option for early-stage CC (Cohen et al. 2019). Concurrent chemoradiotherapy (CCRT) represents a well-established treatment modality for locally advanced CC, and this approach is associated with improved patient survival (Matsuzaki et al. 2020). However, this regimen can result in chronic morbidity and adverse events, and the outcome of patients remains suboptimal (Naga Ch et al. 2018, Burmeister et al. 2022). Accordingly, it remains imperative to explore novel, effective treatment methods to prolong the survival time of patients and improve their quality of life.
Social media in dermatology: clinical relevance, academic value, and trends across platforms
Published in Journal of Dermatological Treatment, 2019
Logan C. DeBord, Viraat Patel, Tara L. Braun, Harry Dao
With such a large proportion of the young adult population communicating information on the Internet, it is advantageous for healthcare providers to keep abreast of social commentary on common conditions. However, much of this commentary is unregulated and contains misinformation that might be interpreted as fact. One study queried five keywords related to acne and collected data from a two-week period in order to determine the relative frequency of ‘high-impact’ tweets (those that were retweeted at least once). It found that of 8192 high-impact tweets, personal tweets about acne were nearly twice as common than those pertaining to education or celebrities (56), confirming the widespread use of Twitter to vent frustrations about acne. The subcategory of education-related tweets included oft-made assertions that both stress and makeup are primarily responsible for pimples, as well as advocating for unconventional or food-based home remedies (56). Practitioners who are aware of the prevalence of information sharing in public forums such as Twitter, whether that information is accurate or based in myth, may be better equipped to tailor individual advice to their patients.
Related Knowledge Centers
- Acne
- Antibiotic
- Bacteria
- Comedo
- Papule
- Puberty
- Sebaceous Gland
- Skin Condition
- Anti-Inflammatory
- Over-The-Counter Drug