Diseases of Infancy and Childhood
Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang in Roxburgh's Common Skin Diseases, 2022
Neonatal acne develops due to excessive sebum production from hormonal stimulation of the sebaceous glands and possible colonization by the Malassezia species. The differential includes neonatal cephalic pustulosis, TNPM, ETN, nevus comedonicus, milia, miliaria, and sebaceous hyperplasia. Medical therapy is generally not required, and the use of daily cleansers with water may be all that is needed. Neonatal acne typically resolves within 3–6 months. In persistent or more inflammatory cases, a low-strength (2.5–5%) benzoyl peroxide gel or topical antibiotic (e.g., erythromycin gel) could be employed.
Punctate porokeratosis—pruritic and hyperkeratotic papules on the palms and feet
Published in Baylor University Medical Center Proceedings, 2020
Patrick Michael Jedlowski, Gina Rainwater, So Yeon Paek
Other clinical entities may mimic PP, including keratosis puncta of the palmar creases, arsenical keratosis, and nevus comedonicus. Keratosis puncta of the palmar creases is a benign condition and variant of punctate keratoderma that occurs most commonly in African American patients. It is typified by hyperkeratotic pits limited to the palmar creases, as opposed to the diffuse palmoplantar lesions in our patient. Arsenical keratosis occurs due to chronic ingestion of arsenic most commonly via contaminated well water and presents with pigmentary changes of truncal skin and mucous membranes, palmoplantar keratosis, and Mee’s lines of the nails.9 Arsenical palmoplantar keratoses range in clinical appearance from indurated, gritty millimeter palmoplantar papules to yellow, verrucous papules and plaques.9 On histology, arsenical keratosis is characterized by compact hyperkeratosis and a thickened stratum granulosum but lacks the columns of parakeratosis seen in our case.9 Nevus comedonicus is a hamartomatous growth of the pilosebaceous unit distinguished by dilated follicles with pigmented, keratinaceous plugs and histopathology displaying epidermal invagination, hyperkeratosis and follicular plugging, which is not seen in this case.
Non-pharmacologic approaches for hidradenitis suppurativa – a systematic review
Published in Journal of Dermatological Treatment, 2021
Aleksi J. Hendricks, Penelope A. Hirt, Sahil Sekhon, Alexandra R. Vaughn, Hadar A. Lev-Tov, Jennifer L. Hsiao, Vivian Y. Shi
Friction was implicated as a predisposing factor in a pediatric patient with HS-like lesions in an inguinal nevus comedonicus, which appeared only when the patient began to crawl (27). In a 28-year-old man with ectopic HS on the dorsal foot, history included working in a right-legged kneeling position while wearing a new pair of shoes (28). A 44-year-old man developed deep inflammatory abscesses and fistulas on his leg stump due to friction from a prosthesis (29). A 33-year-old obese woman presented with classic HS at the frictional site of her bra edge (30).