Chronic cutaneous lupus erythematosus (discoid lupus erythematosus)
Leonard C. Sperling, Shawn E. Cowper in An Atlas of Hair Pathology with Clinical Correlations, 2003
The term ‘chronic cutaneous lupus erythematosus’ (CCLE) is preferred to ‘discoid lupus erythematosus’ (DLE) because it is more inclusive. Nevertheless, DLE enjoys such common usage that the two terms are used interchangeably. CCLE usually occurs in adults, and is more common in women. Although lesions of CCLE are often found in patients with systemic lupus erythematosus (SLE), the majority of patients with CCLE do not have systemic disease. Among patients with skin disease only, about 50% will have scalp lesions, and very few of these patients will ever progress to SLE. Although itching or tenderness is common, the condition may be asymptomatic. The presence of lesions outside the scalp gready simplifies diagnosis.
Recurrent Annular Erythematous Lesions Reactivating at Identical Skin Sites
Rachael Morris-Jones, Ann-Marie Powell, Emma Benton in 100 CASES in Dermatology, 2011
This chapter presents a case study of a 40-year-old woman. A 40-year-old woman is referred to the dermatology clinic with a history of erythematous skin lesions appearing on her face, neck and chest over the past six weeks. The patient complains of a burning and slight itching with the onset of new lesions that then settle over a few weeks leaving marked pigmentation on her skin. Intermittently she has developed new lesions in addition to old lesions flaring. There are multiple annular hyperpigmented macular lesions on the skin over her face, neck and upper chest. The patient was diagnosed with a fixed drug eruption (FDE), which is an interesting phenomenon where exposure to a particular medication leads to annular erythematous skin lesion(s) which heal with pigmentation. The morphology of the skin lesions in FDE is somewhat variable, however. Classically they are circular or oval, macular or bullous and heal with pigmentation.
An Erythematous Rash and Muscle Weakness
Rachael Morris-Jones, Ann-Marie Powell, Emma Benton in 100 CASES in Dermatology, 2011
This chapter presents the case study of a 59-year-old woman. A 59-year-old woman visited her GP as she was concerned about unexplained weight loss. Her GP noted an erythematous rash around her eyes and over the dorsum of her hands and referred her to the dermatology clinic. On direct questioning she does complain about difficulty in getting up out of a chair and climbing the stairs. She denies any other symptoms apart from a persistent dry cough. She is a life-long smoker and drinks alcohol socially. She has erythematous flattish papules over the extensor surfaces of her interphalangeal and metacarpal phalangeal joints. In the periorbital region she has a violaceous erythema with subtle oedema. There is an erythematous non-scaly macular rash affecting her neck and upper back. Neurological examination reveals proximal limb weakness. Muscle involvement is usually manifest by muscle tenderness and weakness with a proximal myopathy.
Acne erythema improvement by long‐pulsed 595‐nm pulsed‐dye laser treatment: A pilot study
Published in Journal of Dermatological Treatment, 2008
Ho Joon Yoon, Dong Hun Lee, Sun Ok Kim, Kyoung Chan Park, Sang Woong Youn
Objectives: Recent studies have demonstrated that pulsed‐dye laser (PDL) treatment is beneficial for inflammatory acne treatment. However, persistent erythema after inflammatory acne vulgaris (‘acne erythema’) remains a therapeutic challenge. The objectives of this study were to evaluate the clinical efficacy and safety of a long pulse duration 595‐nm PDL (V‐beam laser®) therapy for the treatment of acne erythema. Methods: Twenty patients with acne erythema were treated using two successive sessions with a 595‐nm PDL at 4‐week intervals. Overall acne severities were assessed using Leeds scores, degree of improvement using standardized digital photographs, erythema indexes and skin elasticity findings at baseline, and 4 weeks after each treatment. Patients' self‐assessments were also recorded. Results: A total of 90% of acne erythema patients achieved clinical improvement. Lesion counts decreased 24.9% after the first treatment (p
Two cases of annular erythema without bullous lesions by autoimmune blistering diseases
Published in Modern Rheumatology, 2018
Miho Kabuto, Noriki Fujimoto, Toshihiro Tanaka
Although annular erythema is usually observed as one of the cutaneous manifestations of Sjögren’s syndrome or subacute cutaneous lupus erythematosus, autoimmune blistering diseases also present with annular erythema. However, bullous lesions are not always found, and there is a rare type without bullous lesions. We present two cases of autoimmune blistering diseases showing annular erythema without bullous lesions. It is important to perform direct or indirect immunofluorescence examination when we encounter multiple annular erythema.
Quantifying facial skin erythema more precisely by analyzing color channels of The VISIA Red images
Published in Journal of Cosmetic and Laser Therapy, 2016
De-Tian Xu, Jian-Na Yan, Yong Cui, Wei Liu
Background: The VISIA Red images were developed to document and measure facial skin erythema, but diffuse erythema cannot be fully segmented by the VISIA system due to the automatic thresholding segmentation method. Moreover, topical area analysis is not available in the system. Materials and methods: Erythema severity degrees of 20 simulated Red images were designated 1–20 with 1–20 inflammatory lesions for each, respectively. The RGB channel mean values of each simulated image were acquired by ImageJ and relative intensity of red values calculated. Results: The relative intensity of red values positively correlate to erythema severity with a coefficient of 0.999345 (p < 0.001). We also proposed a method for calibration when pustules were present in the erythema area. The method was proved by mathematical reasoning and verified by certified dermatologists. Conclusion: We demonstrated a simple and more precise method to quantify and compare facial skin erythema by analyzing the RGB channel values of the VISIA Red images. Our method brings convenience for erythema evaluation in dermatological studies.