Ayurveda and COVID-19
Srijan Goswami, Chiranjeeb Dey in COVID-19 and SARS-CoV-2, 2022
In Dinacharya, a lot of importance has been given to the hygiene of the mouth, teeth, and gums. The toothpaste that we use should contain certain astringent herbs to keep the teeth tightly held together and the gums healthy. Most Ayurvedic toothpastes do contain these herbs. Cleanliness of the genitals and the anus has been given special attention. Use of water is far better than using toilet paper. There is an elaborate description of the care of all the sense organs with regular use of herbal oils and drops for eyes and ears for better vision and hearing. Gargling with a herbal mouthwash is suggested for oral hygiene and better taste. Special herbs for gargling have been suggested. Gargling thoroughly after every meal is definitely preferable to just wiping the mouth with a tissue. Applying oil to the whole body and keeping it on for ten minutes before taking a bath each morning is the best way to prevent wrinkling of the skin, dry skin, and itching. This is known as Abhyanga. It reduces Vata dosha and helps to keep the skin young and the complexion glowing. It nourishes the muscles, lubricates the joints, and increases body awareness.
3.00: Personal hygiene
Fiona Broadley in Supporting Life Skills for Young Children with Vision Impairment and Other Disabilities, 2020
Children do not need electric toothbrushes, and some may find them disconcerting. However, they can be very attractive to sensory-seeking children. Choose a children’s toothpaste and pay attention to the flavour your child prefers. Many children dislike mint toothpaste, but there are lots of alternatives. A quick check online reveals strawberry, raspberry, bubblegum, melon, berry and ice cream flavours – all easily obtainable – as well as mild mint. For those proving even more sensitive, unflavoured toothpaste is available. Some of these flavours come in bright colours that contrast beautifully with the bristles. It doesn’t matter if your child cannot swap to adult toothpaste. It is more important that he cleans his teeth regularly than uses age appropriate toothpaste. Your dentist can advise if higher fluoride paste would be beneficial.
Environmental Geochemistry and Health in Western Europe
Jul Låg in Geomedicine, 2017
Interest in fluorine centers primarily on its role in dental health. The relationship between fluoride in drinking water and a reduced incidence of dental decay is probably one of the best established links between geochemistry and disease. The link was first recognized in Colorado by McKay,16 who observed an unusual mottling of teeth in his patients, yet these teeth seemed resistant to decay. He also discovered the same condition in immigrants coming from volcanic areas of Italy. It emerged that the common factor was a raised fluoride content of drinking water (2 to 13 mg F per 1). In Britain, unusual mottling was described17 for patients in Maldon, Essex, where only 7.9% of the teeth of children in two of the town’s schools were carious, compared with 13.1% in all districts examined. Water from the Maldon area contained 4.5 to 5.5 mg F per 1, compared with 0.5 mg F per 1 elsewhere. Similar surveys elsewhere in Britain provided similar results. So strong is the relationship that the addition of fluorides to water supplies (to achieve a concentration of 1 mg F per 1) has been undertaken in many countries. But during the period from 1979, especially in western Europe, there has been a marked decline in tooth decay18 which cannot be attributed to fluoridation of water supplies. Toothpaste containing fluoride is now widely available and generally used, and the importance of oral hygiene combined with regular dental checks is better understood.
Protocol with non-toxic chemicals to control biofilm in dental unit waterlines: physical, chemical, mechanical and biological perspective
Published in Biofouling, 2022
Rachel Maciel Monteiro, Viviane de Cassia Oliveira, Rodrigo Galo, Denise de Andrade, Ana Maria Razaboni, Evandro Watanabe
In dentistry, the use of high concentrations of citric acid has been associated with antimicrobial activity. Its effectiveness is attributed to the low pH that acts as a chelating agent (Georgopoulou et al. 1994). Sodium bicarbonate, another lower toxicity chemical, is frequently employed as a cleansing agent by its ability in loosening debris and dissolving mucus (Moharamzadeh 2017). Toothpastes containing a concentration of 20% or more of sodium bicarbonate enhance mechanical plaque removal and improved gingival health (Ghassemi et al. 2020). It has already been reported that a high concentration of sodium chloride increases the external osmotic pressure that may perturb water efflux and dehydration (Wood 2015). Hypertonic saline solution is capable of inhibiting replication of SARS-CoV-2 by disturbing ionic interactions (Machado et al. 2021). Taking these aspects into consideration, it has been hypothesized that a protocol with increased anti-biofilm action could be achieved when associating citric acid, sodium bicarbonate and sodium chloride.
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Krzysztof M. Zak, Mark J. Bostock, Irena Waligorska, Ida B. Thøgersen, Jan J. Enghild, Grzegorz M. Popowicz, Przemyslaw Grudnik, Jan Potempa, Miroslaw Ksiazek
In conclusion, our findings not only confirmed that mirolysin latency is achieved by the “cysteine-switch” mechanism but also significantly improved our knowledge about this secretory protease from T. forsythia. First, mirolysin zymogenicity is exerted by Cys23 in the NTP, which provides latency for promirolysin for several days. Mutation of Cys23 also decreases thermal stability and resistance to proteolysis of the protein. Second, mirolysin possesses extreme thermophilicity, reaching its optimal activity at 65 °C. Third, through NMR-based screening of a fragment library, we identified cpd 9, which is a very selective and competitive inhibitor of mirolysin. Cpd 9 inhibits mirolysin activity with a Ki of 3.2 µM and maturation of promirolysin into an active protease. The solved crystal structure reveals that cpd 9 binds to the S1′ subsite of the substrate-binding pocket in a manner similar to the peptide in the mirolysin–product complex. Based on the solved structure of the mirolysin–cpd 9 complex, in the future, the inhibitory potency of cpd 9 could be improved by fragment growing. Such a compound, together with inhibitors against the most relevant proteases secreted by periodontopathogens, may be used not only in the treatment but also in the prevention of periodontitis. Compounds of such a preventative character could be added to existing oral care products such as toothpaste, mouthwash, or even chewing gum.
In vivo evaluation of fluoride and sodium lauryl sulphate in toothpaste on buccal epithelial cells toxicity
Published in Acta Odontologica Scandinavica, 2019
Antonija Tadin, Lidia Gavic, Tanja Govic, Nada Galic, Nada Zorica Vladislavic, Davor Zeljezic
The study included 40 participants, aged between 20 and 26 (mean age 23.18 ± 1.48). Subjects were divided into two groups. The first group consisted of 20 subjects (14 females and 6 males), aged 21–26 (mean age 23.60 ± 1.54 years). The second group also included 20 subjects (14 females and 6 males), aged 20–24 (mean age 22.75 ± 1.33 years). The first group used three different types of toothpaste of the Sensodyne brand (GlaxoSmithKline, London, UK): Sensodyne Classic, Sensodyne Fluor, and Sensodyne Advanced Clean. While examiners in the second group used three different types of toothpaste of the Plidenta brand (Neva Ltd., Osijek, Croatia): Plidenta15 Seconds, Plidenta Sensitive, and Plidenta Superfresh. Ingredients for different kinds of toothpaste are presented in Table 1. All respondents used the same toothbrush during the research (Colgate Slim Soft, Colgate – Palmolive Company, USA).
Related Knowledge Centers
- Dentifrice
- Fluoride
- Gingivitis
- Oral Hygiene
- Tooth Decay
- Toothbrush
- Tooth
- Dental Plaque
- Bad Breath
- Active Ingredient