Gestational Weight Gain and Postpartum Obesity
Priyanka Bhatt, Maryam Sadat Miraghajani, Sarvadaman Pathak, Yashwant Pathak in Nutraceuticals for Prenatal, Maternal and Offspring’s Nutritional Health, 2019
Trigonella foenum-graecum, commonly referred to as fenugreek, is an erect annual herb from the soy family that originated from India and North Africa. [46, 47] This has been used as a galactogogue historically, the reason being that it contains significant levels of phytoestrogens. Diosgenin is a phytoestrogen that is believed to be responsible for an increase in milk flow. [42] Habitually, fenugreek tea is prepared by brewing the seeds in boiling water for 20 minutes and it is consumed. This ingredient is also an excellent weight loss supplement, as fenugreek seeds contain saponins and alkaloids as well as soluble dietary fibers, which help increase the feeling of satiety, reducing the wish to eat throughout the day. [46] These seeds have also demonstrated hypoglycemic and hypolipidemic effects in multiple preclinical and clinical studies, as summarized by Parveen Kumar and Uma Bhandari in the review titled “Common medicinal plants with ant obesity potential: A special emphasis on fenugreek.” [48]
The Effects of Fenugreek on Controlling Glucose in Diabetes Mellitus
Dilip Ghosh, Prasad Thakurdesai in Fenugreek, 2022
Fenugreek (Trigonella foenum-graecum L.) is an angiosperm plant from the Fabaceae family. It is also known as bird’s foot and Greek hay and is originated to the Mediterranean, southern Europe, Asia and North Africa; however, it is now grown in many parts of the world including northern Africa, India and the United States (5–7). Fenugreek seed has a long history of use for nutritional value and for a broad range of therapeutic effects, including labour induction, indigestion and as a general tonic to improve metabolism and health (8). It has been suggested for the management of hyperglycaemia by several traditional and folklore medicines around the world, especially in Asian traditional medicines including Ayurvedic, Chinese and Persian medicines (9–11).
Anticancer Properties of Silver Nanoparticles from Root Extract of Trigonella Foenum-Graecum
Megh R. Goyal, Preeti Birwal, Santosh K. Mishra in Phytochemicals and Medicinal Plants in Food Design, 2022
Fresh healthy plant roots of Trigonella foenum-graecum (L) were collected, thoroughly washed in purified water, air-dried for several days, and pulverized into a fine powder. Twenty grams of this taken in a conical flask was dissolved in 200 mL of distilled sterile water and mixed with 1 mM of silver nitrate (AgNO3); the solution was mixed well for a few minutes and then incubated 30 min in a water bath, and filtered in Whattman (No. 1) paper and then extract was collected using as reducing agent and stabilizer. The color change observed from neutral to brown at pH 11.0 exhibited the formation of AgNPs. After this, solution was centrifugated for 20 min (5000 rpm) to collect the precipitate, which was air dried and powdered for nanocharacterization by using UV–Vis., SEM, dynamic light scattering (DLS), zeta potential, XRD, and FTIR analysis.
Anti-Inflammatory Subfractions Separated from Acidified Chloroform Fraction of Fenugreek Seeds (Trigonella foenum-graecum L.)
Published in Journal of Dietary Supplements, 2018
Mostafa Pournamdari, Ali Mandegary, Fariba Sharififar, Ghazaleh Zarei, Rahele Zareshahi, Amir Asadi, Mohammad Mehdipour
Trigonella foenum-graecum L. (fenugreek) is a herbaceous plant from the Fabaceae family, and its seeds have different properties such as hypolipidemic, antioxidant, and anticholinesterase effects (Sharma & Choudhary, 2016; Satheeshkumar et al., 2010; Venkata, Bagchi, & Bishayee, 2017). In a clinical trial on patients with type 2 diabetes, consumption of fenugreek seed caused significant decrease of fasting blood sugar (FBS) and very low density lipoprotein (VLDL) in comparison to placebo. In another study, on 60 non–insulin diabetic patients, fenugreek seeds reduced VLDL and low density lipoprotein (LDL), which is useful for atherosclerosis prevention (Kassaian et al., 2009). There are several reports citing the anti-inflammatory effect of this plant that suggest it is a promising candidate for further studies to find new therapeutic compounds (Sharma et al., 2017; Pandaran Sudheeran et al., 2016; Pundarikakshudu et al., 2016). However, safety of this plant has been reported (Deshpande et al., 2017). In an earlier preliminary study, anti-inflammatory effect of different fractions obtained from liquid-liquid extraction of fenugreek seed has been reported (Sharififar, Khazaeli, & Alli 2009; Mandegary et al., 2012). Among these fractions, acidified chloroform fraction (ACC) of the plant exhibited potent inhibition of carrageenan-induced paw edema in mice (Mandegary et al., 2012).
Influence of a Novel Food-Grade Formulation of Red Chili Extract (Capsicum annum) on Overweight Subjects: Randomized, Double-Blinded, Placebo-Controlled Study
Published in Journal of Dietary Supplements, 2021
Ashil Joseph, MSc, Febi John, PhD, Jestin V. Thomas, MSc, Syam Das, PhD Sivadasan, Balu Maliakel, PhD, Ratheesh Mohan, PhD, Krishnakumar I. M.
The safety and bioavailability of the formulation of red chili extracted capsaicinoids from CAP formulation may be attributed to the physicochemical properties of fenugreek dietary fiber and its sustained release. Fenugreek, a popular kitchen spice generally soluble dietary fiber composed of 1:1 ratio of galactose and mannose (galactomannans) (Nathiya and Durga 2014; Yadav and Baquer 2014). A formulation of curcumin with fenugreek fiber has been shown to produce submicronised colloidal particles of curcumin with mucoadhesive character and better membrane permeability and hence bioavailability (Krishnakumar et al. 2012). The high molecular weight and sterically hindered molecular conformation of fenugreek galactomannans were sufficient to produce amphiphilic gels with both water and oil binding characteristics suitable for the impregnation of hydrophobic molecules in its conformationally defined hydrophobic pockets. The gum-like character and film-forming capacity of fenugreek galactomannans provided good encapsulation of the molecules like curcumin and capsaicin for better protection in the gastrointestinal tract. The beadlet form of capsaicinoids impregnated fenugreek fiber with surface coatings could completely protect the pungent molecules in the upper gastrointestinal tract and provided a sustained delivery in the lower intestine/colon for better absorption.
Differences in male climacteric symptoms with aging among rotating night shift workers
Published in The Aging Male, 2020
Sachiko Kubo, Toshiyuki Yasui, Yukie Matsuura, Masahito Tomotake
The proportion of men in the present study who reported sexual symptoms was small, but the proportion increased with advance of age. In addition, there were significant differences in AMS scores for sexual symptoms between men in their 30 s and those in their 40 s and between men in their 40 s and those in their 50 s. Kobayashi et al. [22] reported that mean sexual AMS scores were 12.9 in men who received medical examinations and 15.6 in men with male climacteric symptoms. The mean AMS score for sexual symptom in the present study was 7.5, and this level was lower than that in the previous study [22]. Haider et al. [25] reported that AMS scores decreased in a testosterone-treated group, suggesting that testosterone therapy is effective for improvement of sexual function and quality of life. In addition, Rao et al. [26] reported that treatment with Trigonella foenum-graecum seed extract improved sexual function in middle-aged and older men. Medical treatment should be considered for night shift workers with sexual symptoms.
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