Lessons to Be Learnt from Ayurveda
D. Suresh Kumar in Ayurveda in the New Millennium, 2020
The term nutraceutical is well-defined as “a food or a part of food that provides medical or health benefits including the prevention and treatment of a disease”. However, the term does not represent the perfect terminology in the market and may refer not only to a supplement in the diet, but also to its role in the prevention and treatment of a disease or a disorder. The term nutraceutical was defined by Stephen DeFelice from the combination of the terms nutrition and pharmaceutical in 1989 (DeFelice 1995; Baragi et al. 2008). Herbal nutraceuticals are powerful tools for maintaining health and they act against nutritionally induced acute and chronic diseases, by promoting optimal health, longevity and quality of life (Khan et al. 2014).
Treatments and Challenges
Franklyn De Silva, Jane Alcorn in The Elusive Road Towards Effective Cancer Prevention and Treatment, 2023
Nutraceuticals have engendered interest in the cancer field as a result of their multitargeted properties, relative safety, availability, and reduced cost relative to pharmaceuticals [1312, 1317]. The term, nutraceutical (“nutrition” and “pharmaceutical”), was coined in 1989 by Stephen DeFelice and refers to any entity that provides physiological benefit and/or protection against disease that is a food or part of food [1312, 1317]. This term has been used to refer to dietary supplements, herbal products, specific diets, and processed foods that are nonnutritional and used as medicine [1318]. It has been suggested that nutraceuticals may help prevent chronic diseases, improve health, improve life expectancy, delay the aging process, and help body structure and function [1318]. They may also help to prevent or treat cancer [7, 1034, 1318].
Marine-Based Carbohydrates as a Valuable Resource for Nutraceuticals and Biotechnological Application
Se-Kwon Kim in Marine Biochemistry, 2023
Nutraceutical is a mixed term derived from the words nutrition and pharmaceutical to meet the increasing demand of nutritional supplements with enhanced medicinal values and developed therapeutic agents for selective potential health benefits with minimum toxicity. Nutraceuticals consist of naturally obtained food and supplements with antimicrobial, antioxidant, anti-inflammatory, and antitumor activities and immense health benefits. Nutraceuticals comprise a variety of nutritional products which are physiologically beneficial with great effects on diseases (Ogle et al., 2013). They include dietary supplements, phytochemicals, medical foods, functional foods, and specific dietary patterns. On the basis of chemical constituents, it is classified as polyphenols (anthocyanins, flavonoids, isoflavones, coumarins, lignins, tannins), isoprenoid derivatives (carotenoids, saponins, terpenoids, tocopherols, tocotrienols), carbohydrate derivatives (ascorbic acid, non-starch polysaccharides, oligosaccharides), amino acid derivatives, structural lipids and fatty acids, microbes (prebiotics, probiotics), and micronutrients (minerals, vitamins) (Singh et al., 2020). Here we focus on carbohydrates obtained from marine animals (crustaceans like crabs and shrimp), such as chitosan, and sulfated polysaccharides from marine algae (brown algae), which play a tremendous role in various biological activities as nutraceuticals.
Development of self-microemulsifying drug delivery system for oral delivery of poorly water-soluble nutraceuticals
Published in Drug Development and Industrial Pharmacy, 2018
Ankita V. Shah, Heta H. Desai, Prajwal Thool, Damon Dalrymple, Abu T. M. Serajuddin
A nutraceutical is considered to be food or part of a food that has medical or health benefit, including the prevention and treatment of disease [1]. The definition includes products like isolated nutrients, dietary supplements, genetically engineered designer food, herbal products, processed and functional food, etc. [1]. The global market for nutraceuticals has increased greatly in recent years due to increased consciousness among people to lead healthy lives. There is also a strong desire among certain segments of the general public to supplement the daily nutritional need with nutraceuticals to prevent chronic diseases related to their deficiency. Ease of access to information regarding nutraceuticals and health foods through internet and social media also helped in popularizing them. The global nutraceuticals market was estimated to be US $183 billion in 2015, which is expected to grow to US $279 billion by the end of 2021, with a cumulative annual growth rate of 7.3% from 2015 to 2021 [2]. Due to such a dominant role of nutraceuticals in health care, it is essential to optimize formulations to provide the optimal benefit to humans.
Adulteration and Counterfeiting of Online Nutraceutical Formulations in the United States: Time for Intervention?
Published in Journal of Dietary Supplements, 2018
Mohamed Ismail Nounou, Yamin Ko, Nada A. Helal, Jeremy F. Boltz
Nutraceuticals are health-promoting formulations, usually free from active pharmaceutical ingredients and sold with the therapeutic claim of enhancing different physical and mental activities of the body (Gulati et al., 2006). Furthermore, most nutraceutical formulations are sold with the claim of being 100% natural (Hendset et al., 2005; Johnson and Landry, 1998; Nicoletti, 2012). A nutraceutical formulation is practically a chimera, molding food and drug into a single formulation, which is neither a food nor a pharmaceutical product (Andlauer and Fürst, 2002). However, it is a broader term that involves vitamins, minerals, amino acids, herbs, and botanicals (Dickinson, 2011). Consequently, both dietary supplements and fortified food products can be categorized as nutraceuticals (Bass, 2011).
Nutraceuticals - shedding light on the grey area between pharmaceuticals and food
Published in Expert Review of Clinical Pharmacology, 2018
Antonello Santini, Ettore Novellino
To mark the difference existing between food supplements and nutraceuticals, a proper starting step could be the identification of an appropriate epidemiological target. While food supplements are addressed to compensate, if any, a lack of micro/macro nutrients in the body, a nutraceutical must have a proven pharmacological effect and rationale to be used in a pathological condition. Nutraceuticals are generally reported to have good safety profile with few unwanted side effects and better bioavailability, even if new studies stress the possible adverse effects of both food supplements and nutraceuticals with reference to interactions with pharmaceuticals and/or food [4]. Their application area ranges from metabolic syndrome and inflammation control to Alzheimer’s disease [5–11]. The adoption of nutraceuticals in daily diet may help to prevent the onset of pathological conditions by possibly delaying or avoiding the need to use pharmaceuticals in subjects who qualify for an alternative non-pharmacological approach to a pathological condition.
Related Knowledge Centers
- Ageing
- Dietary Supplement
- Enzyme
- Life Expectancy
- Amino Acid
- Health Claim
- Food Additive
- Drug
- Chronic Condition
- Vitamin