Plant Source Foods
Chuong Pham-Huy, Bruno Pham Huy in Food and Lifestyle in Health and Disease, 2022
The oil extracted from flaxseed is often called linseed oil and has been widely used for non-culinary purposes. Flaxseed oil has become a popular dietary supplement because of its reputed health-promoting properties. Flaxseed is a cultivar of Linum usitatissimum (family Linaceae). The fatty acid profile of flaxseed oil is largely comprised of polyunsaturates (66%), primarily the omega-3 fatty acid alpha-linolenic acid (ALA) (over 50%), and it is this that makes the oil oxidize rapidly (273). The oil also contains 440–588 mg/100 g of tocopherols. Flaxseed oil may reduce platelet aggregation for the prevention of blood clots and may improve autoimmune disorders. However, excessive intake of flaxseed supplement may cause hemorrhage. Due to its low oxidative stability, it has little use in food preparation.
Fats, Fatty Acids, and Lipids
Luke R. Bucci in Nutrition Applied to Injury Rehabilitation and Sports Medicine, 2020
Other studies also found various degrees of clinical benefits after fish oil supplementation to patients with RA,429,432,433 Thus, a consensus of research strongly indicates that supplementation with large doses of EPA + DHA (as fish oil or ethyl esters) possesses some benefits as adjuncts for RA therapy (see Table 6). Results are slow to appear, but suggest a reduction of inflammatory processes and their symptoms, rather than a disease-modifying activity. Possibly, fish oils may offer an alternative to patients with gastric intolerance to standard NSAIDs, since almost no toxicity was found in n3 fatty acid-supplemented groups. Some areas of future research to make application of fish oils more practical include a low fat diet without NSAIDs, since mixed diets or diets high in PUFAs (which were used in all studies) have considerable linoleate and arachidonate contents, which suppress n3 fatty acid conversions to eicosanoids. Likewise, NSAIDs reduce eicosanoid synthesis as their major mechanism of action. The use of flaxseed (linseed) oil, which is almost 50% α-linolenate (the dietary precursor for EPA and DHA), as a source of n3 fatty acids has not been studied in human inflammatory conditions.
Catalog of Herbs
James A. Duke in Handbook of Medicinal Herbs, 2018
Seed yields 57 to 80% of inedible, semi-drying oil, liquid at ordinary temperatures, solidifying at - 15°C, containing oleostearic acid. Said to be the most perfect drying oil known2 the oil is quicker drying than linseed oil, and is used as a wood preservative, for varnishes and paint oil, also as an illuminant, for soap making, and for waterproofing paper; in India for rubber substitutes and insulating masses. Seeds are moderately poisonous, and press cake is used as fertilizer. Seeds are thrown into rivers to stupefy fish.16 Kernels when roasted and cooked, are considered edible; may be strung as candlenuts. Oil is painted on bottoms of small craft to protect against marine borers. Tung oil, applied to cotton bolls, stops boll weevils from eating them. Also prevents feeding by striped cucumber beetle.
Eicosapentaenoic Acid Improves Cisplatin-Induced Muscle Atrophy Without Accompanying Body Weight Gain
Published in Nutrition and Cancer, 2019
Kazumi Yoshizawa, Mayumi Tashiro, Shiori Tezuka, Mizuki Uchiyama, Eiji Uchida, Takeshi Yamada
N-3 polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been identified as promising nutrients with numerous clinical benefits. EPA reduces inflammation and potentially modulates nutritional status and body composition (12). Although, the mechanism is not fully understood, it is well known that EPA inhibits NF-κB activation (13). In this study, we investigated the effects of EPA on CDDP-related loss of muscle mass in mice. In this study, we used olive oil and linseed oil as control. Olive oil contains approximately 70% oleic acid (n-9 fatty acid). On the other hand, linseed oil contains approximately 50% alpha-linolenic acid (n-3 fatty acid).
Aceclofenac oil drops: characterization and evaluation against ocular inflammation
Published in Pharmaceutical Development and Technology, 2018
Rajesh Katara, Sameer Sachdeva, Dipak K. Majumdar
Linseed oil alone inhibited the inflammatory responses in a significant manner (p < .05) as compared with its control. Linseed oil, from the plant Linum usitatissimum, is composed of omega 3–57%, omega 6–16%. Ratio of 1:3 of omega 3: omega 6 is considered to be close to ideal (Roncone et al. 2010). Linseed oil is given orally as an adjuvant therapy in patients in dry eye diseases. In a study, topical use of omega 3 and omega 6 showed successful control of inflammatory symptoms in mice with induced keratoconjunctivitis sicca (Rashid et al. 2008; Parrilha et al. 2015).
Overcoming hydrolytic degradation challenges in topical delivery: non-aqueous nano-emulsions
Published in Expert Opinion on Drug Delivery, 2022
Arya Kadukkattil Ramanunny, Sachin Kumar Singh, Sheetu Wadhwa, Monica Gulati, Bhupinder Kapoor, Rubiya Khursheed, Gowthamarajan Kuppusamy, Kamal Dua, Harish Dureja, Dinesh Kumar Chellappan, Niraj Kumar Jha, Piyush Kumar Gupta, Sukriti Vishwas
Linseed oil, which is considered as a rich source of polyunsaturated fatty acids, was explored by Tou et al. [28]. They formulated co-enzyme Q10 loaded nano-emulsion cream using unsaturated oils such as linseed, evening primrose, and olive oil. In the ex vivo skin permeation study, highest permeation of co-enzyme Q10 was observed with the formulation containing linseed oil. This was attributed to the presence of omega 3 fatty acid in linseed oil which acted as a permeation enhancer [28].
Related Knowledge Centers
- Dietary Supplement
- Flax
- Resin
- Liquid–Liquid Extraction
- Linoleum
- Alkyd
- Cooking Oil
- Α-Linolenic Acid
- Omega-3 Fatty Acid
- Triglyceride