Managing Diabetes without Weight Gain
David Heber, Zhaoping Li in Primary Care Nutrition, 2017
Diets high in monounsaturated fat (MUFA) (Parillo et al. 1992; Rasmussen et al. 1993; Campbell et al. 1994; Walker et al. 1996) result in improvements in glucose tolerance and lipids compared with diets high in saturated fat. An important caveat is that adding fat to the diet adds calories, so added olive or avocado oil should be used to enhance taste by spraying them on fruits, vegetables, and whole grains, rather than liberally spooning these fats into recipes. A meta-analysis has found that high-MUFA diets reduce fasting glucose in patients with T2DM (Schwingshackl and Strasser 2012). Diets enriched with MUFA may also reduce insulin resistance (Parillo et al. 1992). There is, however, concern that when high-MUFA diets are eaten ad libitum outside of a controlled setting, they may result in increased energy intake and weight gain (Yu-Poth et al. 1999). A recent meta-analysis of nine randomized controlled intervention trials with a total of 1547 participants and a running time of at least 6 months compared high- and low-MUFA diets among adults with abnormal glucose metabolism (T2DM, impaired glucose tolerance, and insulin resistance), being overweight or obese. It was found that high-MUFA diets appear to be effective in reducing HbA1c, and therefore should be recommended in the dietary regimes of T2DM (Schwingshackl et al. 2011). More studies comparing diets high in MUFA with diets high in carbohydrate with ad libitum energy intake are needed to evaluate the efficacy of these diets and determine the effects of MUFA in reducing cardiovascular risk in diabetes.
Coronary Artery Disease
Stephen T. Sinatra, Mark C. Houston in Nutritional and Integrative Strategies in Cardiovascular Medicine, 2022
One final disturbing reason is the processing of canola oil. Canola and other vegetable oils are extracted from seeds by crushing them and heating them along with chemical solvents, such as hexane. Hexane is derived from petroleum and crude oil; it is used as a cleaning agent in furniture industries, and as an additive in glue and varnishes. The EPA classifies hexane as an air pollutant, and the CDC says it is a neurotoxin. Although vegetable oil manufacturers may suggest that hexane is completely safe, honestly, I am a little skeptical. I prefer an oil that is not heated at high temperatures or goes through a procedure of deodorization. When it comes to oils, I like cold-pressed EVOOs, as no chemical solvents are used and there is minimal processing. So, the question is – what do you cook with? Firstly, I am not a big fan of high-heat frying with any oil as high heat can cause the oil to oxidize, which tends to enhance inflammatory status. If I do use olive oil or organic butter, I prefer a quick sauté in a minimal heat. If higher heats are required, I prefer coconut oil. If you do not like the taste of coconut oil, avocado oil could be another option. Although I tend to keep olive oil away from the frying pan, I use it for “finishing” meals. It is outstanding when it is sprinkled over thinly sliced grass-fed beef, sautéed veggies like broccoli and asparagus, and certainly salads.
Plant Source Foods
Chuong Pham-Huy, Bruno Pham Huy in Food and Lifestyle in Health and Disease, 2022
Avocado is the fruit of the avocado tree, called Persea Americana, family Lauraceae. It is native to Mexico and Central America and is now cultivated in tropical and subtropical climates (Mediterranean area, Central America, South Asia). There are many varieties of avocado; among them, the Hass cultivar is the most commercially popular avocado worldwide (106). The fruits are egg-shaped or spherical and have a dark green skin and a fleshy and creamy body. One-half an avocado (68 g), is a nutrient and phytochemical dense food consisting of the following: dietary fiber (4.6 g), total sugar (0.2 g), potassium (345 mg), sodium (5.5 mg), magnesium (19.5 mg), vitamin A (5.0 μg RAE), vitamin C (6.0 mg), vitamin E (1.3 mg), vitamin K1 (14 μg), folate (60 mg), vitamin B-6 (0.2 mg), niacin (1.3 mg), pantothenic acid (1.0 mg), riboflavin (0.1 mg), choline (10 mg), lutein/zeaxanthin (185 μg), cryptoxanthin (18.5 μg), phytosterols (57 mg), and high-monounsaturated fatty acids (6.7 g), and 114 kcals or 1.7 kcal/g, all of which may support a wide range of potential health effects (106). Avocado oil consists of 71% monounsaturated fatty acids, 13% polyunsaturated fatty acids, and 16% saturated fatty acids, which help to promote healthy blood lipid profiles and enhance the bioavailability of fat-soluble vitamins and phytochemicals from the avocado or other fruits and vegetables, naturally low in fat, which are consumed with avocados (106). Avocado consumption protects the cardiovascular system and eyes, promotes digestion, prevents oxidative stress, slows down age-related degenerative diseases, helps weight management, and supports healthy aging.
Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats
Published in Drug and Chemical Toxicology, 2022
Erdi Onur Gokkaya, Sukriye Yesilot, Meltem Ozgocmen, Rahime Aslankoc, Cigdem Aydin Acar
Due to the unique taste and aroma of avocado, its oil is commonly used in the food industry. Aside from the food industry, avocado oil is used in the cosmetics industry on account of its content. Avocado oil also plays a pivotal role in the protection of human health as a result of containing single-chain unsaturated oleic acid and reducing the level of low-density lipoprotein (LDL) cholesterol in the blood, thereby reducing the likelihood of atherosclerotic heart diseases. In addition, avocado oil has been reported to exert a protective effect against cardiovascular diseases due to its high antioxidant content, its high levels of vitamins A, B, and E, and its high soluble fiber content when compared with other foods.
Optimization of nutraceutical coenzyme Q10 nanoemulsion with improved skin permeability and anti-wrinkle efficiency
Published in Drug Development and Industrial Pharmacy, 2018
Eman S. El-Leithy, Amna M. Makky, Abeer M. Khattab, Doaa G. Hussein
CoQ10 was kindly donated as a gift from Mebaco Company, Cairo, Egypt. Tween 80 with the hydrophilic/lipophilic balance (HLB = 15), Span 20 (HLB = 8.6), olive oil, sodium lauryl sulfate (SLS), Tween 20, oleic acid, ethanol, and isopropanol (HPLC grade) were purchased from El-Nasr Pharmaceutical Chemical Company, Cairo, Egypt. Avocado oil was obtained as a gift from (Jan Dekker Nederland B.V, Wormerveer, Holland). Caproyl 90, Labrasol (HLB = 14), Labrafil M1944 and Transcutol HP (HLB = 4.2) were given as a gift from Gattefosse (Cedex, France). Cremophor EL (HLB = 13.5), isopropyl myristate (IPM) and propylene glycol (HLB = 4.45) were purchased from Sigma-Aldrich, Germany.