Nutritional and Dietary Supplementation during Pregnancy
“Bert” Bertis Britt Little in Drugs and Pregnancy, 2022
Reflux esophagitis results in heartburn or pyrosis and esophageal erosion is very common in pregnancy. It is thought to be secondary to decreased gastroesophageal sphincter tone, with resultant gastric acid reflux. Reflux therapy consists primarily of one of the antacid preparations discussed in the previous section. Frequent small feedings and elevation of the head at night may be beneficial. H2-receptor antagonists or PPI (omeprazole or esomeprazole) as well as metoclopramide may prove effective for severe forms of reflux. Esomeprazole and omeprazole are the most popular treatments for reflux esophagitis. Omeprazole and esomeprazole are sufficiently well studied during pregnancy to reasonably state they are safe.
Gastritis and Gastric Ulcers
John F. Pohl, Christopher Jolley, Daniel Gelfond in Pediatric Gastroenterology, 2014
Gastrointestinal: – Constipation.– Gastroesophageal reflux/reflux esophagitis.– Nonulcer dyspepsia.– Cholecystitis.– Inflammatory bowel disease.– Pancreatitis.
Sleep–Wake Disorders
Philip B. Gorelick, Fernando D. Testai, Graeme J. Hankey, Joanna M. Wardlaw in Hankey's Clinical Neurology, 2020
Differential diagnosis includes: Hypoglycemia.Peptic ulcer disease.Reflux esophagitis.Kluver–Bucy syndrome.
Localization of Helicobacter pylori gastritis and the relation of existing histopathological features with reflux esophagitis
Published in Scandinavian Journal of Gastroenterology, 2020
Serkan Yalaki, Hüseyin Pulat, Aysu Ilhan
The major mechanism of reflux esophagitis (RE) contains the decline in basal pressure of the lower esophageal sphincter (LES), and increment in the frequency of spontaneous transient relaxation of the LES. The acid level of reflux content (i.e. pH <4) is also a critical risk factor for the formation of esophageal mucosal damage. It has been suggested that Hp may contribute to GERD through different mechanisms; such as the development of antral gastritis that increases acid production, a decrease in LES pressure and a deterioration of gastric filling [11]. However, the decrease in the incidence of Hp infection and related diseases (such as peptic ulcer and gastric cancer) in the Asian countries is associated with an increased incidence of GERD and associated complications. These epidemiological data support the protective role of Hp rather than its causal role for reflux disease [1,2].
Endoscopic treatment can be a viable therapeutic option for esophageal gastrointestinal stromal tumors
Published in Scandinavian Journal of Gastroenterology, 2022
Haojie Du, Longgui Ning, Hongtan Chen, Fengling Hu, Guodong Shan, Wenguo Chen, Guoqiang Xu
There were no significant differences in gender, age, symptoms, tumor location, tumor size, mitotic index, and adjuvant imatinib therapy between the surgery group and the endoscopic treatment group (all p > .05) (Table 2). The main clinical characteristics, therapeutic outcomes, and follow-up outcomes of these 20 patients were listed in Table 3. Five patients experienced temporary infection or fever after treatment. One patient with esophagectomy experienced reflux esophagitis. The mean follow-up period of the surgery group and the endoscopic treatment group was similar (70.8 ± 50.0 vs. 50.2 ± 27.9 months, p = .260). During the follow-up period, one patient in the surgery group exhibited disease recurrence and accepted adjuvant imatinib therapy, while no recurrence was observed in the endoscopic treatment group. The patient with local tumor recurrence underwent a tumor enucleation with a mitotic index of 5/50 HPF, which was slightly higher than that of other patients. The Kaplan-Meier curve suggested that there was no significant difference in disease-free survival between the surgery group and the endoscopic treatment group (p = .264) (Figure 3).
Effect of anti-reflux treatment on gastroesophageal reflux-associated chronic cough: Implications of neurogenic and neutrophilic inflammation
Published in Journal of Asthma, 2020
Norihisa Takeda, Masaya Takemura, Yoshihiro Kanemitsu, Hisatoshi Hijikata, Kensuke Fukumitsu, Takamitsu Asano, Yusuke Yamaba, Motohiko Suzuki, Eiji Kubota, Takeshi Kamiya, Takashi Ueda, Akio Niimi
All participants underwent esophageal endoscopy for the assessment of reflux esophagitis by expert endoscopists. The grade of the severity of the esophagitis was evaluated according to the latest version of the Los Angeles classification with a slight modification (22). Reflux esophagitis (erosive GERD) was divided into 4 grades as follows: Grade A, one (or more) mucosal breaks no longer than 5 mm; Grade B, mucosal break longer than 5 mm, extending between the top of two mucosal folds; Grade C, continuous mucosal break between the tops of two or more folds but not involving 75% of the esophageal circumference; and Grade D, mucosal break involving at least 75% of the circumference. Minimal change esophagitis (Grade M) and no endoscopic abnormalities (Grade N) were defined as non-erosive reflux disease (NERD) (22–24).
Related Knowledge Centers
- Dysphagia
- Heartburn
- Odynophagia
- Esophagitis
- Esophageal Stricture
- Barrett'S Esophagus
- Obesity
- Pregnancy
- Smoking
- Hiatal Hernia