Cardiovascular Imaging for Early Detection of Coronary Artery Disease
Ayman El-Baz, Jasjit S. Suri in Cardiovascular Imaging and Image Analysis, 2018
CMRA can precisely assess the abnormal origin of coronary arteries and the location and dimensions of coronary artery aneurysms. This is facilitated by the larger caliber and the proximal location of the coronary artery aneurysms (CAA). The most important benefit of CMRA is the absence of ionizing radiation, which is of special clinical value for children and women [105, 107] (2, 4). Diseases characterized by ectatic or aneurysmatic coronary arteries are Kawasaki disease, autoimmune vasculitis, and coronary artery ectasia [108–111] (5–8).
The STENTYS self-apposing stent technology in coronary artery disease: literature review and future directions
Published in Expert Review of Medical Devices, 2018
Huangling Lu, Robbert J. De Winter, Karel T. Koch
The incidence of coronary artery ectasia varies between 1.5% and 5% during coronary angiography in large registries [11,12]. There is an overlap of this condition with coronary artery aneurysms, which is more focal in nature, in the literature. Coronary aneurysm is generally defined as localized or segmental dilatation that exceeds the diameter of normal adjacent segments by 1.5 times [13]. The mechanism of the development of coronary ectasia or aneurysm is not yet fully understood. A potential cause of coronary artery ectasia is outward remodeling due to atherosclerosis, which is found in more than 50% of cases. Other contributing factors are connective tissue disease, Kawasaki disease, inflammatory arterial diseases, infectious causes, congenital coronary artery disease, and idiopathic or secondary to PCI procedures [14,15]. Isolated coronary ectasia or aneurysms are associated with a long-term mortality rates that vary from 15% to 29% at 1 and 5 years, respectively[16]. Data on patient outcome after PCI of stenotic lesions involving coronary artery ectasia or aneurysm is limited to case reports. Patients could benefit from the nitinol platform, which is able to appose to the aneurysmatic coronary artery wall as demonstrated in a model as well as in vitro using stent boost (Figure 2).
Comparison of systemic immune-inflammation index levels in patients with isolated coronary artery ectasia versus patients with obstructive coronary artery disease and normal coronary angiogram
Published in Scandinavian Journal of Clinical and Laboratory Investigation, 2022
Kerim Esenboğa, Alparslan Kurtul, Yakup Yunus Yamantürk, İrem Müge Akbulut, Durmuş Eralp Tutar
Coronary artery ectasia (CAE), an abnormality of the coronary anatomy, has been defined as localized or diffuse nonobstructive lesions of the epicardial coronary arteries, with a luminal dilatation 1.5 or more times greater than the diameter of the adjacent normal portion of the artery [1]. Isolated CAE is defined as CAE without significant coronary artery stenosis. Isolated CAE is a form of coronary atherosclerosis associated with risks of death and myocardial infarction, equivalent to that of patients with obstructive coronary artery disease (CAD) [2,3]. The underlying precise mechanism responsible for ectasia formation has not been established, however its common co-existence CAD has raised the idea that CAE is a variant of CAD. In the most of cases, it has been attributed to atherosclerosis based on shared common links [4,5]. Inflammation has been reported to be an important component of vascular aneurysm formation [6,7].
A giant coronary artery ectasia successfully managed conservatively
Published in Journal of Community Hospital Internal Medicine Perspectives, 2020
Waqas Ullah, Mishal Shaukat, Asrar Ahmad, Zain Ali, Maryam Mukhtar, Mamoon Ur Rashid
Approximately 0.9% to 4.9% of the patient population undergoing coronary angiography are found to have CAA and it is more commonly seen in men. Right coronary artery (RCA) is the most common site for CAA [1]. The most common cause of CAA is atherosclerosis; followed by Kawasaki disease, polyarteritis nodosa, systemic lupus erythematosus, infection, trauma, angioplasty, and congenital malformations. Coronary artery ectasia can also occur as a complication of coronary artery stenting and has been increasingly reported as a complication of drug-eluting stenting [2]. Here we present an idiopathic case of CAA with a surprisingly giant size which presented with chest pain. Our patient denied a history of vasculopathy, Kawasaki disease, connective tissue disorders and chest trauma making the diagnosis very challenging.
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