A Brief History of Pain from a Personal Perspective
Mark V. Boswell, B. Eliot Cole in Weiner's Pain Management, 2005
My own work started in 1958, while I was a member of the New York University Rheumatic Diseases Study Group. Specifically the question was raised whether it is possible to (1) measure a patient’s pain level objectively and (2) predict a given patient’s ability to tolerate (clinical) pain during physical rehabilitation and postoperative exercises of an operated joint. Obviously, with that background and at that time, the emphasis was on deep somatic arthritic pain rather than on cutaneous or visceral pain. Consequently, I chose to utilize a strictly psychophysical approach to devise a technique and measure the patient’s pain response. Pain threshold determinations had been made by earlier investigators, such as von Frey (1897), on the skin, culminating in the “heroic” studies of Hardy, Wolff, and Goodell (1952), who used themselves as guinea pigs to measure pain threshold and pain discrimination with radiant heat on the skin. They developed the Dol scale of pain and introduced the radiant heat dolorimeter. Their work can be regarded as the first major psychophysical study of human pain. However, at that time, less psychophysical information existed for deep somatic tissues.
The Sexual Victimization of Patients with Functional Somatic Syndromes
Peter Manu in The Psychopathology of Functional Somatic Syndromes, 2020
The fourth investigation exploring the link between sexual abuse and psychopathology in fibromyalgia was performed at the University of Alabama, Birmingham (Alexander et al., 1998). The authors recruited 75 women who had been diagnosed with fibromyalgia after being evaluated by the staff of the outpatient rheumatology clinic. Criteria for inclusion were age between 18 and 65 and the absence of other rheumatic disorders or chronic fatigue syndrome. The assessment of sexual and physical abuse relied on a seven-item interview similar to that used by Boisset-Pioro and colleagues (1995). Psychiatric disorders were identified with the computerized version of the Diagnostic Interview Schedule (Blouin et al., 1988). Self-administered questionnaires measured the severity of pain and fatigue, health-related quality of life, coping strategies, and daily environmental stress. Objective evaluations with a dolorimeter assessed the threshold for perceiving pain at 10 musculoskeletal sites.
Brief History of Multidisciplinary Management of Chronic Pain, 1900–2000
Michael E. Schatman, Alexandra Campbell, John D. Loeser in Chronic Pain Management, 2007
The subjects reported their initial sensation of pain (threshold) and maximum tolerance of the stimulus to establish their baselines and then were tested under aspirin, morphine, codeine, and other analgesics. Changes in threshold and tolerance under analgesia were measured in terms of stimulus intensity and duration. The dolorimeter method made it possible to develop quantitative and graphic comparisons of the available analgesics. However, many of the volunteers need to go through a series of trials to learn how to best report changes in perceived sensation: “untrained subjects, even of high intelligence, cannot be used successfully” in such experiments (10–12).
Protective effect of gastrodin on peripheral neuropathy induced by anti-tumor treatment with vincristine in rat models
Published in Drug and Chemical Toxicology, 2021
Bingjie Qin, Ni Luo, Yuxing Li, Denghui Gong, Jun Zheng, Xiao Tan, Weihong Zheng
Mechanical allodynia was assessed using a Von Frey test on day 0, 7, 14, and 21. The rats were adapted to the assessment situation for at least 30 min prior to initiation of stimulation. During the assessment, rats were placed on a mesh steel wire, covered with organic glass, and Von Frey electronic dolorimeter (VonFrey electronic dolorimeter 2390, America IITC) was used to sting one of the rats’ post planta pedis, each filament was presented perpendicularly against the paw, with sufficient force to cause slight bending for 2–3 seconds. The stimulation threshold was recorded with rats reaction like licking foot or foot lifting, repeated three times with an interval of 15 minutes, then the average value was calculated as the mechanical hyperalgesia value of rats.
Algometry for the assessment of central sensitisation to pain in fibromyalgia patients: a systematic review
Published in Annals of Medicine, 2022
Pablo de la Coba, Casandra I. Montoro, Gustavo A. Reyes del Paso, Carmen M. Galvez-Sánchez
This systematic review was conducted according to the guidelines of the Cochrane Collaboration and reported based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) [40]. The inclusion criteria and analyses were specified in advance, and the protocol was registered in the Prospective Register of Systematic Reviews (PROSPERO) international database (registration ID: CRD42021270135). The search string was as follows: central pain sensitisation AND fibromyalgia AND (algometry OR algometer OR dolorimetry OR dolorimeter OR evoked OR experimental OR elicited OR testing OR pressure OR mechanical OR thermal OR heat OR electrical OR cold).
Related Knowledge Centers
- Epigastrium
- Palpation
- Tail Flick Test
- Skin
- Pain
- Analgesic
- Threshold of Pain
- Carbon-Dioxide Laser
- Randall–Selitto Test
- Hot Plate Test