Lymph Node
Joseph Kovi, Hung Dinh Duong in Frozen Section In Surgical Pathology: An Atlas, 2019
A 56-year-old man was seen at the clinic with complaints of a non-tender mass in the right inguinal area of 3 weeks duration. On examination, the superficial inguinal lymph nodes on the right side were found considerably enlarged, but not painful. No systemic symptoms were noted. A biopsy was taken. The node measured 15 by 9 by 9 mm and was moderately firm. Microscopically, the basic architecture of the lymph node was intact. The subcapsular, the cortical, and the medullary sinuses were markedly distended by macrophages with abundant pale pink, often vacuolated cytoplasm, and tiny, round nuclei. Some of the macrophages contained brown, granular pigment. No other changes of significance were found (Figure 83).
Vesicles
Giuseppe Micali, Pompeo Donofrio, Maria Rita Nasca, Stefano Veraldi in Vulval Dermatologic Diagnosis, 2015
Clinical aspect: Primary herpes simplex (HS) is characterized by significant morbidity, long duration, general symptoms (fever, malaise, and myalgia), and significant local pain. After an incubation period ranging from 1 to 3 weeks, multiple and often clustered vesicles of approximately 0.5–0.8 mm in diameter, surrounded by erythema and edema, appear on the labia, vaginal introitus, and perineal area (Figures 4.1.1 and 4.1.2); subsequently, blisters may erode, leaving polycyclic abrasions (Figures 4.1.3 through 4.1.5) or shallow and tender ulcers (Figures 4.1.6 and 4.1.7). Frequent cervical and urethral involvement causes vaginal and urethral discharge, dysuria, and, sometimes, urinary retention. Inguinal lymph nodes are enlarged and tender.
Lower limb
David Heylings, Stephen Carmichael, Samuel Leinster, Janak Saada, Bari M. Logan, Ralph T. Hutchings in McMinn’s Concise Human Anatomy, 2017
Inguinal lymph nodes - about 15 or so, lying superficially along the great saphenous vein and inferior to the nearby part of the inguinal ligament (Fig.8.4), with two or three deep to the deep fascia beside the femoral vein. Efferent channels pass from these deep nodes through the femoral canal to the external iliac nodes. Apart from draining the whole of the lower limb (including the gluteal region), the nodes receive lymph from the trunk wall (front and back) below the umbilical level and from the perineum, thus including the lower vagina and anal canal.
Urethral stricture and scrotal abscess: a rare case presentation of penile cancer and review of the literature
Published in The Aging Male, 2020
Aldo Franco De Rose, Francesca Ambrosini, Laura Tomasello, Francesco Boccardo, Carlo Terrone
The clinical condition of the patient got worse: he developed pelvic, scrotal, and perineal pain and both the scrotal volume and the purulent urethral discharge increased. The patient received antibiotic treatment without response. An abdominopelvic revaluation CT showed a penile solid mass of 5 cm × 8 cm × 9 cm extending from the glans to the root of the penis, infiltrating the corpus cavernosum and the spermatic funiculus. Enlarged bilateral inguinal lymph nodes were identified measuring about 13 mm. Furthermore, suspected small lymph nodes were detected along the external iliac vessels. A surgical Emasculation was performed in February 2018: penis in toto, urethra, and both testicles were removed. Histopathologic examination demonstrated a well-differentiated keratinizing SCC of penis with positive margins of resection (pT4/G1-2).
Squamous cell carcinoma of the vulva: a review of present management and future considerations
Published in Expert Review of Anticancer Therapy, 2019
Vulvar cancer affects the female external genitalia, including the labia majora, labia minora, clitoris, introitus, and urethral meatus. Primary lesions arise in one of these anatomical areas, and metastatic disease can occur in three ways. One is by direct extension to adjacent external structures such as the vagina or anus. Another is spread to inguinal lymph nodes. Data from lymphatic mapping studies show that over 97% of lymphatic drainage will go directly to the superficial inguinal nodes with the small remaining portion spreading to the deep inguinal nodes [38]. Either of these routes can occur relatively early in disease progression. The third way vulvar cancer can metastasize is through hematogenous dissemination. This typically occurs late in the disease process and rarely happens without metastatic disease already in the lymph nodes.
Vulvar acrochordons arranged in a linear pattern
Published in Journal of Obstetrics and Gynaecology, 2018
Sanjay Singh, Alok Kumar Sahoo, Neetu Bhari, Savita Yadav
A 32-year-old woman, gravida 2 para 2, presented with multiple, asymptomatic, pedunculated, soft polypoidal growths of size ranging from 2 mm to 2.5 cm, arranged in a linear array over the left vulva for the past 20 years’ duration. Over the past 20 years, lesions had gradually increased in number and size. The patient gave no history of generalised skin tags anywhere else over the body or in any of the family members. She had no significant medical or family history. Her menstruation cycles were regular. There was no past history of any other genital lesion and she also denied history of extramarital sexual exposure. Her routine blood investigations including fasting blood sugar and lipid profile were normal. Systemic examination was within normal limits. Integumentary examination revealed an involvement of left vulva in the form of multiple linearly arranged soft, fleshy, skin coloured to hyper pigmented pedunculated polypoidal growths, which were more discrete at the upper and lower part, and were closely aggregated in the middle part (Figure 1(a)). No overlying surface changes were seen. Inguinal lymph nodes were not enlarged. Per speculum examination did not reveal grossly apparent lesions on (normal appearing) vaginal walls and exocervix. No underlying sinus or communication was observed between the lesion and the vagina wall.
Related Knowledge Centers
- ADDuctor Longus Muscle
- Groin
- Inguinal Ligament
- Lymph Node
- Sartorius Muscle
- Thigh
- Femoral Triangle
- Fascia of Camper
- Femoral Vessel
- Saphenous Opening