- Shrinkage
- Shunt
- Shut-in
- Shutdown
- Shutter glasses
- Shuttle valve
- Shuttle vector
- SiGe
- SiP
- Sial
- Sialic acid
- Sialon
- Siberian High
- Sibutramine
- Sick building syndrome
- Sickle cell disease
- Side chains
- Side effects
- Side population
- Side reactions
- Side valley
- Side-channel attacks
- Side-scan sonar
- Side-stick
- Side-valve
- Sidebands
- Sidelobes
- Siderite
- Sideroblastic anemia
- Siderophores
- Siderosis
- Sideslip
- Sidestream smoke
- Sidewalk
- Siding
- Siemens NX
- Sierpinski Carpet
- Sierpinski Triangle
- Sierra Nevada Batholith
- Siesta
- Sieve analysis
- Sievert
- Sieverts' law
- Sieves
- Sight glass
- Siglec
- Sigma bonds
- Sigma factor
- Sigmatropic rearrangement
- Sigmoid function
- Sigmoidoscopy
- Sign bit
- Sign convention
- Sign extension
- Sign function
- Sign test
- Signal analyzer
- Signal averaging
- Signal conditioning
- Signal corps
- Signal flow
- Signal generators
- Signal integrity
- Signal peptide
- Signal processing
- Signal reconstruction
- Signal reflection
- Signal regeneration
- Signal separation
- Signal strength
- Signal subspace
- Signal trace
- Signal transition
- Signal transition graphs
- Signal transmission
- Signal velocity
- Signal-flow graph
- Signal-to-interference ratio
- Signal-to-interference-plus-noise ratio
- Signal-to-noise plus interference
- Signal-to-noise ratio
- Signal-to-quantization-noise ratio
- Signaling
- Signaling protocol
- Signalling
- Signature recognition
- Signcryption
- Signed
- Signed distance function
- Signed graphs
- Signed measure
- Significant figures
- Significant wave height
- Signs and symptoms
- Silane
- Silanes
- Silanization
- Silanol
- Silastic
- Silcrete
- Silence
- Silent
- Silent mutations
- Silhouettes
- Silica
- Silica fiber
- Silica fume
- Silica gel
- Silica sulfuric acid
- Silica-alumina
- Silicalite
- Silicate minerals
- Silicate weathering
- Silicates
- Silicene
- Siliceous limestone
- Siliceous ooze
- Siliceous rock
- Silicic
- Silicic acid
- Siliciclastic
- Silicides
- Silicification
- Silicon
- Silicon alkoxide
- Silicon carbide
- Silicon carbide fibers
- Silicon dioxide
- Silicon drift detector
- Silicon monoxide
- Silicon nanotubes
- Silicon nanowires
- Silicon nitride
- Silicon oxycarbide
- Silicon oxynitride
- Silicon photomultiplier
- Silicon photonics
- Silicon quantum dots
- Silicon retina
- Silicon steel
- Silicon tetrachloride
- Silicon tetrafluoride
- Silicon-oxygen bond
- Silicone
- Silicone grease
- Silicone oil
- Silicone resin
- Silicone rubber
- Silicosis
- Silk